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Topina (Topiramate)

Topina is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and decrease how often you get them. Topina will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room). Topina is known as an anticonvulsant or antiepileptic drug.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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The PBL was delivered within a rural retreat and included site visits. pH-Responsive Capsules Engineered from Metal-Phenolic Networks for Anticancer Drug Delivery. We conclude that TOC1 is an important component of the circadian clock in Arabidopsis with a crucial function in the integration of light signals to control circadian and morphogenic responses. Evidence-Based Parenting Programs for Maltreating Parents: Views of Child Protective Services Caseworkers.

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The question of gene patentability has raised some opposition in France. We searched all databases from their inception with no restriction on language.

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Mature virions were seen in the nuclei of infected Chang cells, but not in human embryo kidney cells, indicating that at least a proportion of Chang cells can support the entire replicative cycle. Elevation of intracellular divalent cation concentrations, by ionophore A23187, induced release of lysosomal enzymes but this was a result of cell lysis. Requirements for the processing of antigen by antigen-presenting B cells. Visible strabismus influences negatively the ability to obtain a job. The successful merger of theoretical thermochemistry with fragment-based methods in quantum chemistry.

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Thus, the therapeutic goals primarily include the maintenance of proper blood supply and prevention of hypoxic condition in liver, along with management of factors responsible for high blood ammonia, oxidative stress, inflammation, and high GI- serotonin. Understanding the medical past through literature: bloodletting and the Louisiana swamp doctor.

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Hunger perception and stunting among children living in poor conditions from the north of Argentina Frameshifting (FS) indels and nonsense (NS) variants disrupt the protein-coding sequence downstream of the mutation site by changing the reading frame or introducing a premature termination codon, respectively. To report a patient with bilateral choroidal metastasis from a malignant paraganglioma.

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Taken together, our results reveal the true impact of IS elements on the diversification of bacterial genomes and highlight their novel role in genome evolution. The greatest dimension of the enlarged nodes ranged from 0.5 cm to 2.5 cm and the nodes were most frequently located at level V.

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First report of Bluetongue virus isolation in the Republic of Korea and analysis of the complete coding sequence of the segment 2 gene. We investigated the effect of aldosterone and spironolactone, which is a non-selective mineralocorticoid receptor antagonist, on monocyte chemoattractant peptide (MCP-1) and collagen synthesis in cultured mesangial and tubular epithelial cells.

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Selective ET(A) antagonist, but not ET(B) antagonist, reduced the ET-1 content as well as the NADPH diaphorase activity, and preserved the fine structure of LV myocardium in cardiomyopathic hamsters. Non-adherent and semi-adherent cells are assayed by centrifugation of plates before fixation. Higher operating temperature, excess air ratio, and lower moisture of sludge are beneficial to reduce the formation of hazardous organic pollutants BTEX (benzene, toluene, ethylbenzene, and xylene) and PAHs (polycyclic aromatic hydrocarbons), but increase the emission of fine particulate. Survival of freeze-dried leuconostoc mesenteroides and Lactobacillus plantarum related to their cellular fatty acids composition during storage.

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These antibodies can be divided into four groups according to such criteria as localization of the recognized epitopes and reactivity with p53 originating from other organisms. All women referred to Weston Park Hospital, Sheffield, with GTD between 1st January 1996 and 31st December 2000. The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever.

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This study was conducted to compare the effect of adding fentanyl to epinephrine-containing lidocaine on depth and duration of local anesthesia in painful maxillary molars with irreversible pulpitis (IRP). A greater proportion of P2-derived transcripts was observed when cells changed from exponential to stationary growth or if cultures were grown in minimal medium. Despite the small number of patients and different types of surgeries performed, laparoscopic management of iatrogenic lesions seems to be feasible and safe in experienced hands. Insights into the crystal growth mechanisms of zeolites from combined experimental imaging and theoretical studies. HCV positivity should not exclude appropriate candidates for CLKT.

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Thus the vitelline layer of the fertilized egg could be involved in preventing sperm penetration into the egg without being altered structurally or functionally. B19 IgG and IgM antibodies were assessed by ELISA, and the presence of B19 DNA was evaluated by nested PCR. In addition, our results also demonstrated that long-term combination treatment with aspirin and ABT-737 could synergistically induce apoptosis both in A549 and H1299 cells. Whether a difference in morphology of the infratentorial space is associated with hemifacial spasm is not well understood. The condition of intervertebral fusion and clinical effect were respectively assessed by X-ray films and JOA score.

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It is concluded that relatively low dietary RNA concentrations decrease food intake and growth and cause enlarged kidneys which contains many crystals composed mainly of calcium salts. To determine long-term survival in patients with status epilepticus (SE). These findings suggest that deoxyschizandrin and gamma-schizandrin-induced apoptosis in HL-60 cells involved ROS-independent mitochondrial dysfunction pathway. The simulated time-domain characteristics of modulation include the waveforms of the intensity and frequency chirp as well as the associated distortions of the modulated mm-wave signal. The purpose of this study was to report the evolution of coronary artery calcification (CAC) in subjects with chronic kidney disease Stages 3 and 4 comparing those with and without diabetes.

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The mean subjective IKDC score rose from 43.6 to 84.0, and the Lysholm score rose from 62.1 to 90.8. Adjuvant chemotherapy after resection of liver metastases from colorectal cancer.

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We evaluated the use of computerized quantification of wheezing and crackles compared to a clinical score in assessing the effect of inhaled albuterol or inhaled epinephrine in infants with RSV bronchiolitis. The published results of a 3 year population study of acute viral hepatitis provided an opportunity to assess the completeness of routine reports of laboratory confirmed acute hepatitis B and their validity as indicators of incidence.

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In general, pedobarography showed an unloading of the first toe with a load transfer to the metatarsal heads on the operated side. The sample was represented by 5,564 diabetics referred for eye checks.

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Superoxide anion production, chemotaxis and phagocytic activity were studied in peritoneal macrophages obtained from young (2 months old) and aged (24 months old) rats. Anti-phosphatidylethanolamine antibodies, anti-annexin antibodies, and factor XII deficiency were more common factors in recurrent spontaneous abortion patients than were anti-cardiolipin antibodies in terms of induction of recurrent pregnancy losses. Our objective was to assess the effectiveness of these teams with respect to client outcomes. Moreover, this study can also be used to elucidate the defence responses of the genes that were of plant origin. The mineralocorticoid-dependent hypertension possesses particular characteristics in humans and animals.

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Previous studies demonstrated that the development kinetics and growth factor responsiveness of hematopoietic precursors derived from embryonic stem cells (ES cells) is similar to that found in the yolk sac, indicating that the onset of hematopoiesis within the embryoid bodies (EBs) parallels that found in the embryo. Aspergillus fumigatus forms biofilms with reduced antifungal drug susceptibility on bronchial epithelial cells. Digital retinal photographs of both eyes were taken in 2001 and graded for retinal vascular caliber, vertical optic disc diameter, and vertical cup-to-disc ratio (CDR) according to standardized protocols.

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Axon growth is a highly regulated process that requires stimulating signals from extracellular factors. Fifty-five healthy subjects were studied prospectively during the first year of life on two isocaloric diets that differed only in their protein content: the first one supplied 2.5 gm/kg/day of protein and the second supplied 4.0 gm/kg/day. Internal structure of a mitochondrial intron of Aspergillus nidulans. Cases registered by 6 Australian treatment centers for the acute care and rehabilitation of SCI patients. Hib conjugate vaccine delivered through the national immunisation programme is very effective in reducing Hib meningitis in children under 5 years of age.

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The expression levels of membrane CXCR4 on HS/PCs were assessed by flow cytometric analysis (FACS). Proteolysis of CCL26 by chymase and tryptase, respectively, released distinct fragments of the COOH- and NH2 -terminal regions. Fifteen patients underwent extended left lobectomy, one patient an extended left lateral lobectomy, and nine patients right lobectomy.

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Self-collection tools for routine cervical cancer screening: a review. Positive immediate skin tests in cystic fibrosis: a possible role for Pseudomonas infection. Alpha actinin distribution and extracellular matrix products during somitogenesis and neurulation in the chick embryo.

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Significant amounts of volatile organic compounds and greenhouse gases are generated from wastewater lagoons and tailings ponds in Alberta, Canada. There is sufficient working space for the endoscope and all instruments, allowing for endoscopic assistance and bimanual surgical technique. Activity ratios, thermostability, genetic localization and comparison with two other thermostable variants. Coupling between phosphate release and force generation in muscle actomyosin. Compared with pre-training, at 6 months of follow-up, nurses were significantly more likely to ask about smoking status, assess readiness to quit, advise to quit, assist with quitting, and arrange follow-up.

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Pulmonary arterial hypertension is defined by a pressure of at least 25 mmHg. Since the cloning of Aequorea victoria green fluorescent protein (GFP) in 1992, a family of known GFP-like proteins has been growing rapidly. These conclusions are at variance with the results obtained in the TDDFT approximation for the asFP595 chromophore. In an earlier retrospective pilot study, we found hints that individuals were snoring less in a lateral versus a supine head position.

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In enterobacteria, GlnD uridylylates the PII proteins GlnB and GlnK under low levels of fixed nitrogen or ammonium. It will not, however, fulfil the need for subspecialty-based training required to cope with the large minority of patients necessitating complex surgical intervention. Anticonvulsants are used in clinical practice for the treatment of PTSD. Pharmacokinetic profiles were assessed on nine occasions during a 24-week period. To date, only four cases of neurosarcoidosis have been reported in association with TNF inhibitors, two of which were attributed to etanercept.

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In actual medical practise COP is notably measured in adult intensive care patients to control oncotic fluid therapy. Participants were randomly assigned to receive either acyclovir, 400 mg twice daily for 70 days, followed by a 14-day washout period, and then placebo for 70 days, or the study medications in the reverse order. Long-term randomized trials of growth hormone therapy, however, remind us of the persisting short stature and significant adult height deficit in untreated children without early spontaneous catch-up.

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A model of chronic schistosomiasis, in mice, to study its interaction with Salmonella infection Here, we show the potentials of simian TRIM5alpha and APOBEC3G as therapeutic sequences for AIDS gene therapy.

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Moreover, interference with isoprenylation underlies many of the beneficial actions of the statins on vascular endothelium, which include increased endothelial nitric oxide synthase expression, pro-angiogenic effects, increased fibrinolytic activity, immunomodulatory and anti-inflammatory actions, including increased resistance to complement. The efficacy of switch therapy in community-acquired pneumonia in Japan Single-marker analysis using 322 molecular markers segregating among RIL detected a total of 38 linked markers for each genetic factor and heading in the field. Multiple sclerosis (MS) relapses have been associated with viral and bacterial infection epidemics in MS patients who have not used interferon. Since the boundary conditions are written in terms of velocities, vector boundary integral equations are obtained for solving the problem.

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Mean frequency, angle of the trend in instant frequency as well as 3 nonlinear parameters-spectral entropy, approximate entropy, and Higuchi fractal dimension- are calculated to characterize the spindle waveforms. Afferent fibers communicated with dendrites and somata of CRF-immunoreactive neurons via both symmetrical and asymmetrical synapses.

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We present a case of a highly functioning 41-year-old Navy Commander with sporadic Creutzfeldt-Jakob disease, to include the diagnostic challenges, rapid clinical deterioration, and limited treatment options. Validity of a New Quantitative Evaluation Method that Uses the Depth of the Surface Imprint as an Indicator for Pitting Edema.

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Utility of real-time shear wave elastography for assessing liver fibrosis in patients with chronic hepatitis C infection without cirrhosis: Comparison of liver fibrosis indices. The fine dust fractions are enriched by lead, zinc and arsenic oxides. Specific activity of phospholipase A2 is enhanced 5-fold while specific activities of lysolecithin acyltransferase and lysolecithin : lysolecithin acyltransferase are only slightly increased or remain unchanged. Pulmonary alveolar microlithiasis is a rare disease and only 32 cases have been reported in children under 12 years of age.

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Metabolic changes in blood and skeletal muscle of dogs before, during and after tourniquet ischaemia were investigated to obtain further information on cellular metabolic abnormalities and restitution during and following long-lasting blood flow interruptions. Effects of acute exhaustive exercise and chronic exercise training on type 1 and type 2 T lymphocytes. Genomic DNA extracted from buccal epithelial cells of the included participants were genotyped using a matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry method. Functionally, this was seen as slower contractions and reduced fatigue resistance of eye muscles in animals with strabismus and defects of binocular vision.

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We report the case of a 31-year old woman presenting with atypical rheumatic disease in the 28th week of the second pregnancy. The usefulness of the combined growth hormone (GH)-releasing hormone and arginine stimulation test in the diagnosis of radiation-induced GH deficiency is dependent on the post-irradiation time interval. Understanding the role of grafted polystyrene chain conformation in assembly of magnetic nanoparticles. The technique of routinely culturing endothelial cells from various sources has provided new insights into an unexpected multitude of synthetic and metabolic capacities of these cells, such as the degradation of arachidonic acid, the enzymatic activation of angiotensin I, and many others.

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Hepatic complement receptor clearance function was evaluated by measuring the hepatic uptake of a test dose (2.9 X 10(8)/100 g) of rat erythrocytes coated with anti-erythrocyte immunoglobulin M (EIgM) or EIgG in rats. Specifically, in these patients the lavage underestimated the amount of macrophages in the lung biopsies and overestimated the number of lymphocytes that were present in the lung parenchyma. Se removal from contaminated sites using physical, chemical, and engineering techniques is quite complicated and expensive. In this study, we demonstrated that the 5-HT(2A) receptor subtype is fully expressed in the human choriocarcinoma cell lines JEG-3 and BeWo as well as in normal human placental tissue.

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Bile acids induce activation of alveolar epithelial cells and lung fibroblasts through farnesoid X receptor-dependent and independent pathways. Extreme climatic events (ECEs) such as droughts and heat waves are predicted to increase in intensity and frequency and impact the terrestrial carbon balance. It has been suggested that growth cones navigating through the developing nervous system might display adaptation, so that their response to gradient signals is conserved over wide variations in ligand concentration. Good agreement is found between the experimental results and the model.

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CD14-159C/T polymorphism is not relevant to sepsis mortality in any genetic models, regardless of the ethnicities. The primary outcome for this study is relapse of psychotic symptoms. These findings suggest that the formation of chlorophyll-containing photoreceptor membranes may be paced and stabilized by concurrent synthesis of galactosyl diglycerides. Anticoagulants during pregnancy for mechanical prosthetic valves. ECGF1 mutations cause severe loss of TP activity, abnormal accumulations of thymidine and deoxyuridine in plasma, and alterations of mitochondrial DNA.

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Herd-level factors associated with isolation of Salmonella in a multi-state study of conventional and organic dairy farms I. We anticipate that the technique will be useful as a compact, simple method of generating localizable, subcellular chemical and mechanical signals, compatible with standard microscopy. T2-weighted images and MR signal intensity in normal liver parenchyma and tumor tissue were acquired before and after injection, to assess the MR imaging ability of the microcapsules. We assessed ALT, AST, and HBV-branched DNA to find which is the best for predicting hepatitis activity and fibrosis. These mechanisms must be impaired in amnesics and, in normal subjects, are very sensitive to delay and learning exposure manipulations.

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The fundamental assumption underpinning the evolution of numerous adaptations shown by parasites with complex life cycles is that huge losses are incurred by infective stages during certain transmission steps. ColE1 multimer formation triggers inhibition of Escherichia coli cell division. Effects of site-specific amino acid modification on protein interactions and biological function. We identified genes previously implicated in proliferative control and epithelial cell function including two established tumor suppressors, TGFBR2 and PTEN. A 2-year-old morbidly obese boy presented with early manifestation mylan clindamycin phosphate and benzoyl peroxide gel of vascular disease associated with several obesity-related features of the metabolic syndrome due to massive overfeeding.

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Probe design was adapted to generate species-specific high resolution probe sets that would tolerate repetitive elements. In addition, a presumed alternate transcript of 4.8-5.0 kilobases, which may lack PTP domains, is present in proliferating osteoblasts, but not detectable at other stages. To examine in retrospect prognostic factors influencing meningeal dissemination relapse of medulloblastoma (MB) and to estimate time parameter gamma/alpha of the biologically effective dose for fractionated pyridostigmine bromide tablets gulf war oil craniospinal irradiation (CSI). Average bone mineral density variation was 0.0048 to -0.0264 g/cm2 per year in all five regions in nonoperated hips and -0.012 to -0.0300 g/cm2 in operated hips.

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