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Terbinafine
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Terbinafine

Terbinafine has a fungicidal effect by inhibiting the enzyme squalene monooxygenase which is involved in the synthesis of sterol in fungi. This inhibits fungal sterol biosynthesis by decreasing ergosterol levels. Fungal membranes are not able to grow because ergosterol is one of the main components of the fungal cell membrane. Additionally, squalene accumulates which weakens the cell membrane. Orally, the drug is very effective due to its ability to concentrate within the nails.

Other names for this medication:
Terbinafine, Lamisil,

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Successful transplantation of cyclosporine-treated allograft recipients with serologically positive historical, but negative preoperative, donor crossmatches. In this case average length of MT is equal to the half of cell radius. Skin biopsies from 23 birds with psittacine beak and feather disease (PBFD) were examined by light and electron microscopy. 275 children with VUR 1 found on initial CRC, and 31 children without reflux and with the same clinical history were studied.

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