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The extension to the hierarchical generalized linear model and its use as a multilevel measurement model for dichotomous measurement indicators is demonstrated. The role of endogenous opioid receptors on anterior pituitary hormone secretion was evaluated by the administration of the opioid receptor antagonist naloxone. Efficacy of a new intraaortic propeller pump vs the intraaortic balloon pump: an animal study.

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Complications of these fractures and their management are discussed in this report. We report a rare case of life-threatning pneumothorax induced by multiple intrapulmonary cavitary lesion due to Absidia corymbifera and methicillin-resistant Staphylococcus aureus (MRSA).

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Since regression is a highly complex phenomenon, it would seem reasonable that this will involve multiple biological mechanisms and is unlikely to be due to 1 factor in isolation of others. The purpose of this study was to determine the sites and time to recurrence in patients with clinical stage I NSCLC whose initial staging evaluation included conventional imaging and fluorodeoxyglucose-PET. Single trial behavioral task classification using subthalamic nucleus local field potential signals.

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Whatever the technical solution used, the function preservation that we reported here, was more and more associated with better oncological result, for the patient benefit. The effects of elevated seawater temperatures on Caribbean gorgonian corals and their algal symbionts, Symbiodinium spp. A 17-year-old female presented with a left intraventricular and intraparenchymal cerebral hemorrhage resulting from a 1 cm left posterior choroidal AVM. To determine whether serum levels of potential markers could detect insulin resistance (IR) in young women with polycystic ovary syndrome (PCOS). In addition, stroke severity is closely correlated with decreased TH1/TH2 ratio, increased production of interleukin (IL)-10, with infected stroke patients showing exacerbated production of IL-10.

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Cognitive ability might be linked to the educational gradient through CVD risk factors. Cytotoxicity of cortivazol in childhood acute lymphoblastic leukemia. Identification of brain networks using time-varying spatial constraints of neural activity reconstruction. The manuscript was written by Latremouille-Viau, along with the other authors, and revised by Joseph, along with the other authors.

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We examined whether the transcriptional activation of the rat haptoglobin (Hp) gene during the acute phase (AP) response reflects the O-linked N-acetylglucosamine (O-GlcNAc) status of liver nucleoproteins (NPs) and their binding for the hormone responsive element (HRE). Characterization of the isoflavone pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells. Transverse maxillary hypoplasia, in adolescents and adults, is frequently seen in non-syndromal and syndromal patients including cleft patients. There was a substantial fall in systemic arterial pressure, which was not associated with a compensatory tachycardia. These problems arose firstly because of the large numbers of animals slaughtered to bring the epidemic under control, which meant that the conditions under which animals were slaughtered and the manner in which this was carried out often breached regulations concerning welfare at slaughter.

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Also, because we did not observe an increase in hnRNP-K protein at early time points in the cell cycle in the presence of cycloheximide, we propose that the early increase in cytoplasmic hnRNP-K protein following serum stimulation is due to new hnRNP-K protein synthesis. The patient demonstrated knee strength deficits following ACL rupture and surgery.

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Enhancement of the antiproliferative activity of human interferon by polyamine depletion. The results indicate that supplemental Mo in the amount of 10 mg/L of drinking water inhibited mammary carcinogenesis.

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Inhibition by valproic acid of pyruvate uptake by brain mitochondria. N-ethyl-N-nitrosourea mutagenesis: boarding the mouse mutant express. Little is known about the prevalence of dementia and other disabling conditions among rural centenarians although this information is important to clinicians caring for them. Here, we show that Nodal expression is upregulated in human pancreatic cancer tissues. Further in vivo studies reveal that both 2-MeOE2bisMATE and 2-EtE2bisMATE are orally bioavailable and extremely efficacious when compared to clinically tested drugs.

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Asymptomatic aneurysms of the infrarenal abdominal aorta: should we still be operating? Self-assembly allows for the preparation of highly complex molecular and supramolecular systems from relatively simple starting materials. Neither the overall cancer risk, nor the CRC risk, were increased in this population-based cohort after a median of 19 years of follow-up evaluation. The detection of stable circulating miRNAs in plasma of NPC patients has raised the potential of miRNAs as novel diagnostic markers. This article reviews the current research in the areas of HPS value perceptions and studies of HPS impact on knowledge and knowledge transfer among nurses.

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Roentgen diagnosis of secondary mucocele occurring in the frontal sinuses following radical operation. The Universal Protein Resource (UniProt) is a freely available comprehensive resource for protein sequence and annotation data.

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The second determinant, either on the chromosome of strain JH1 or on an undetectable plasmid, was inducible by tetracycline and enabled the host strain, in the absence of pJH1, to grow in the presence of 80 micrograms of tetracycline per ml. All energy densities of Ar ion laser showed a proliferative effect on Pseudomonas aeruginosa and inhibitory effect on Staphylococcus aureus. Mosaic microecological differential stress causes adaptive microsatellite divergence in wild barley, Hordeum spontaneum, at Neve Yaar, Israel.

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Circulating and bone marrow colony-forming cells are markedly reduced. Ongoing multicenter, international randomized studies comparing percutaneous coronary intervention with DES and bypass surgery will shed more light on the best treatment strategy for ULM coronary disease. Generalized and specific models for maternal/fetal pharmacokinetics were developed.

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The present study demonstrates that Permixon therapy has no negative impact on male sexual function. In the present paper, we report the results obtained, docking these ligands in the binding pocket of HDLP, an HDAC homologue.

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The solubility of a range of metal oxides in a eutectic mixture of urea/choline chloride is quantified, and it is shown that the dissolved metals can be reclaimed from a mixed metal oxide matrix using electrodeposition. Addition of heparin at 10 micrograms/ml abolishes the formation of the 150 kDa complex and does not affect the 135 kDa complex. Efficacy of progesterone following a moderate unilateral cortical contusion injury. Calcium absorption (six studies) did not change during treatment.

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Treatment success may require combining different therapeutic approaches. Neurologic examinations and laboratory assessments were performed every 3 months. Rats receiving a pancreas-duodenum transplantation 2 days earlier, i.e., with graft pancreatitis, were injected with iopromide. Prevalence of Plagiarism in Manuscript Submissions and Solutions.

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Blau syndrome and early-onset sarcoidosis are NOD2 gene-associated chronic autoinflammatory diseases characterized by skin rash, arthritis, and/or eye involvement, with noncaseating granulomata as their pathologic hallmark. When another indazole carboxylic acid derivative, lonidamine, was administered (250 mg/kg), similar changes were evident in epididymal and serum rABP at 32 hours, but the rapid decrease in testicular rABP suggested a different mechanism of action. Establishment of pharmacological evaluation system for non-nucleoside reverse-transcriptase inhibitors resistant HIV-1 Establishing a link between heart rate and pain in healthy subjects: a gender effect. Proteolytic activity of developing dentine of rat tooth germs revealed by the gelatin-film substrate technique.

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Results showed that cumulative food intake was significantly increased by 2MA alone, as compared to saline controls, with most of the 2MA-elicited eating occurring during the first hour post-injection. Therefore, the combined effects of the loss of PTEN lipid and protein phosphatase activity may result in aberrant cell growth and escape from apoptosis, as well as abnormal cell spreading and migration.

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The mechanisms underlying these synergistic effects seem to involve the synergistic enhancement of apoptosis and cooperative attenuation of radiation-induced G(2)-M arrest, possibly via Chk1 and Chk2 inhibition, by the combined drug treatments. Middle cerebral artery mean velocity (CBFV) was measured together with ventilatory parameters and heart rate before, during, and after immersion. Although experimental PPI data have increased significantly over recent years, most PPI networks still have many false positive interactions and false negative edge loss due to the limitations of high-throughput experiments. Molecular analyses of leukemic blasts from patients with acute myeloid leukemia (AML) have revealed a striking heterogeneity with regard to the presence of acquired gene mutations and changes in gene and microRNA expression.

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Immunohistochemical and semiquantitative study of the apical mitochondria-rich cells of the human prepubertal and adult epididymis. An extended analytic expression for the membrane potential distribution of conductance-based synaptic noise. Thermally induced gas flows in ratchet channels with diffuse and specular boundaries.

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Different parvalbumin and GABA expression in human epileptogenic focal cortical dysplasia. The HBx mutant with a combination of CP mutations can up-regulate Skp2, which then down-regulates P53 via ubiquitin-mediated proteasomal degradation, increasing the risk of hepatocellular carcinoma. The isolation of opioid receptor genes opened the way to molecular manipulations of the receptors, both in artificial systems and in vivo, contributing to our current understanding of the diversity of opioid receptor biology at the behavioral, cellular and molecular levels. PATIENTS AND STUDY QUESTIONS: We therefore investigated, in 79 patients who died after intensive care and who did or did not receive thyroid hormone treatment, whether total serum thyroid hormone levels correspond to tissue levels in liver and muscle.

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Hierarchical group names are typically manually assigned in trees, an approach that becomes unfeasible for very large topologies. In the present study, short sleep duration was a positive significant determinant for WMH and PVH in elderly hypertensives. One hundred and eighty-eight patients diagnosed early with thrombophilia were included in the study. It could also be purified in abundance from the cell surfaces of the producer strain. Solution-processable ferroelectric polymer nanocomposites are developed as a new form of electrocaloric materials that can be effectively operated under both modest and high electric fields at ambient temperature.

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Time-course of glutathione peroxidase repletion and lipid peroxidation decrease. Gestational age, mass size and pelvic adhesions were significantly correlated with PEP.

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Symmetrically Substituted Xanthone Amphiphiles Combat Gram-Positive Bacterial Resistance with Enhanced Membrane Selectivity. A telemedicine instrument for home monitoring of patients with chronic respiratory diseases. The results for chicks were in closer agreement with values obtained using the Silcock available-lysine assay (Roach et al. Translation and validation of the Dutch version of the Oxford 12-item knee questionnaire for knee arthroplasty.

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Gleason score at the margin can predict biochemical recurrence after radical prostatectomy, in addition to preoperative PSA and surgical margin status. Proximal enlargment of air spaces was most severe, both subjectively and morphometrically, in those dogs exposed to oxides of nitrogen, oxides of sulfur, or oxides of sulfur with photochemically reacted auto exhause. To find the structural basis and the molecular mechanisms underlying this aging-related network specificity, we also analyzed protein domain interactions and gene expression patterns across different tissues.

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Thirty-seven head injured patients were administered the Recognition Memory Tests on the day that PTA resolved. The frameless procedure is associated with a higher risk for malpositioning of the catheter.

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The adsorption of cationic basic blue 9 and anionic acid orange 51 from aqueous solution onto the calcified eggshell (ES) and its ground eggshell powder (ESP) was carried out by varying the process parameters such as agitation speed, initial dye concentration, adsorbent mass and temperature. The aim of this study was to investigate the influence of systematic training in physical growth and biological maturity in prepubertal males and estimate how this affects the physical growth and skeletal maturity. The current goal of CHB treatment is sustained viral suppression with the aim of reducing or preventing hepatic injury and disease progression. The effect of different doses of oxygen administration on oxygen saturation in patients with stroke. The number of protein families has been estimated to be as small as 1000.

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At the first stage of mass spectrometry, these sequence isomers cannot be differentiated and would appear as doublets rather than singlets. The items explored both core and fourth-year clerkship perspectives.

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Engineering and Characterization of Peptides and Proteins at Surfaces and Interfaces: A Case Study in Surface-Sensitive Vibrational Spectroscopy. The onset and duration of benefit from counselling by minimally trained counsellors on anxiety and depression in women. Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii. Here, we report the complete genome sequence of an H6N8 avian influenza virus (AIV) isolated from wild waterfowl in Poyang Lake, China, in 2016.

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Regulation and function of triacylglycerol lipases in cellular metabolism. There was no evidence that the degree of bronchodilation achieved with ipratropium bromide was greater than that using a short-acting beta2-agonist. Functional potential of soil microbial communities in the maize rhizosphere. High-molecular-weight polyricinoleate, with an M(w) of 100,600, was enzymatically prepared by the polycondensation of methylricinoleate using immobilized lipase from Pseudomonas cepacia (IM-PC) in bulk in the presence of 4 A molecular sieves at 80 degrees C for 7 d. Validation experiments showed that the optimal nitrogen source was composed of 0.28 g/L (NH(4))(2)SO(4), 0.49 g/L KNO(3) and 1.19 g/L beef extract.

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In contrast to mouse FcRn, which binds to IgGs from multiple different species, human FcRn is surprisingly stringent in binding specificity. Percutaneous nephrolithotomy (PNL) is usually performed worldwide with a rigid-only antegrade approach. This finding shows that monensin affects biosynthesis rather than merely disrupting lysosomal degradation that is already deleted with respect to GlcCer in Gaucher disease cells.

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Both patients with the Charles Bonnet syndrome and patients with dementia with Lewy bodies can present with formed visual hallucinations. Insidious symptoms and bodily changes due to pregnancy may mask diagnosis.

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It is clear that the human genome has not undergone such a rapid change, and thus alone does not explain the increased obesity. The results indicate that chromosome 3 carriers gene(s) that control malignancy in Chinese hamster cells in cell lines transformed by a viral or a chemical carcinogen and that malignancy was induced in both cell types by an increase of these genes. One hundred and seven patients with histologically proven nonmetastatic prostate cancer and an elevated prostate-specific antigen (PSA) who were referred for radiation therapy had three serum PSA values obtained prior to the start of definitive therapy. The use of autologous platelet concentrate combined with autogenous and xenogenous grafts allowed fast soft and hard tissue healing. This case highlights the need for a high index of suspicion for pituitary abscess based on unusual imaging findings even when there is no source of infection.

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Preoperative and postoperative general health and function were assessed via the 36-item Short-Form (SF-36) Health Survey and American Academy of Orthopaedic Surgeons (AAOS) Modems Instrument, which were collected prospectively. This did not differ significantly from the 69 per cent response rate for children with ADHD and other neurodevelopmental disorders. We found that resveratrol had a preventive role in the histopathological changes caused by cigarette smoking in the rat trachea. Our study demonstrates that groundnut plant rhizosphere harbors a core microbiome populated by Proteobacteria, Actinobacteria, Firmicutes, Bacteroidetes, and Acidobacteria.

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Highly unusual tubular keratins are pathognomonic of another dominant palmoplantar keratoderma type the genetic basis of which still awaits elucidation. Integrins, dystroglycan, syndecans, and the other several cell surface molecules are cellular receptors for laminins. In a much slower secondary response, both quantities change in the opposite direction, leading to a reversal of the initial change in the conductivity. High dose cyclophosphamide (11 patients) and variations of VAD regimen (7) associated with granulocyte colony stimulating factor were used for peripheral-blood stem cell harvest. A prospective, randomized, controlled multicenter trial comparing stapled hemorrhoidopexy and Ferguson hemorrhoidectomy: perioperative and one-year results.

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APG accelerated the ulcer healing, especially in healing the refractory diabetic cutaneous ulcers, and the high-level growth factors from the platelet releasate were thought to be the major potential mechanism of the APG action. IGF-binding protein-3 (IGFBP-3) can induce apoptosis in human prostate cancer cells by direct, IGF-independent mechanisms that are poorly understood.