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It was unrelated to the use of integrins as rotavirus receptors, as both integrin-using and integrin-independent viruses induced integrin regulation. ODNs delivered locally distributed widely within the brain tumor mass and inhibited TGF-beta2 expression. How cells sense decrease in oxygen levels to elicit an increase in HIF dependent gene expression is not fully understood.

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Independent component analysis of nondeterministic fMRI signal sources. Controlled trials in dual-diagnosis patients are needed to confirm these findings. Carriers of the f allele were significantly more likely to develop BC. The MR imaging findings were compared with the surgical and pathologic findings.

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Clinical consequences can range from no symptoms to severe manifestations including cardiomyopathy, hypoglycaemia, peripheral neuropathy and sudden death. Human 20S proteasome activity towards fluorogenic peptides of various chain lengths. Splenocytes from C57BL/6 mice fed either normal diet or 50 ppm Mg-diet were used as responder cells in mixed lymphocyte reaction (MLR) performed with splenocytes from C3H/He mice (H-2(k), Mls(IIa)) and C57BL/6 mice fed normal diet as stimulators for allogeneic and isogeneic conditions, respectively. Conclusions In cases of lower eyelid ectropion, the surgical outcome after the tarsal strip procedure was similar for absorbable and non-absorbable sutures.

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The Delphi procedure resulted in a comprehensive, operational definition of paratonia. A peculiar type of fat necrosis was noted in some patients with various skin diseases. Vascular relaxation of small mesenteric arteries was measured using myograph. The results provide support for the feasibility of such initiatives.

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The epitope specific for mAb-2B6 recognition is linear, spanning five residues (774)DGXNP(778) in the B/C domains. The aim of this pilot investigation was to evaluate if dental implants placed after extractions in patients with end-stage periodontitis affect the serum CRP levels. Titles from the 78th Annual Meeting of the Japanese Society for Hygiene.

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Clinicians should take a careful history when evaluating patients with ONJ because ONJ may result from one or more factors. In recent years endoscopically controlled laser-induced thermal therapy (LITT) has been increasingly accepted as a minimally invasive method for palliation of advanced or recurrent head and neck or gastrointestinal cancer. Early studies suggest that CR reduces DNA damage by enhancing DNA repair. Fifty-two non-alcoholic cirrhotic patients were evaluated for decompensation component of cirrhosis. Recent theoretical simulations and experimental results suggest that electrostatic steering forces can also be manipulated to increase association rates while leaving dissociation rates unchanged, thus increasing affinity.

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Photochemistry of the alkaloids eudistomin N (6-bromo-nor-harmane) and eudistomin O (8-bromo-nor-harmane) and other bromo-beta-carbolines. The objective of the study was to investigate in these patients SDI and factors influencing the prevalence of fractures. Although penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) were discovered in 1976 in neighbouring countries, not until 1980 were such strains isolated and identified in Indonesia. A common guideline was developed for the management of women with these conditions. While Rab11-FIP1B and F gene transcripts are ubiquitous, other Rab11-FIP1 transcripts demonstrate more limited patterns of expression in human tissue cDNAs.

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The first is controlled by the I-A region alone and the second depends on a pair of alleles, one located to the left of I-B (presumably in I-A) and the other to the right of I-J (presumably in I-E). elegans, most clearly as dramatically decreased reproduction potential. Magnetic capture and lavage evaluate CTXII in different ways: Magnetic capture measures total CTXII in the joint, while lavage measures concentration.

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Mechanism of proliferation of cells transformed by the Moloney mouse sarcoma virus after stable reversion to a non-malignant state Alpha-chain disease with involvement of small intestine-resulting in characteristic villus atrophy and malabsorption has not been reported in this country. We hypothesize that continuous-flow limb hypothermia can reduce paclitaxel-induced PN. Because of ambiguity inherent in FFM profile descriptors, this insufficiency may prove unlikely to be attenuated with increased clinical familiarity with the FFM. Our results indicate that Khat treatment can induce apoptosis through enhancing the release of Smac/DIABLO from the mitochondria to the cytosol after transient focal ischemia which may be an important mechanism of Khat neurotoxicity.

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Student education with using training simulator for endoscopic surgery The performance of ELISAs with the recombinant antigens decorin-binding protein A (DbpA), DbpB, and BBK32 (from Borrelia afzelii, B. Unlike other human and mouse HIN-200 proteins that contain only a single 200 amino acid domain, overexpression of p206 impaired the clonogenic growth of tumour cell lines. We demonstrate the method by quantifying the distribution of an exogenous metal carbonyl complex throughout the cell and by reporting changes in its coordination sphere in different locations in the cell.

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We measured in 9 cirrhotic patients, before and after successful OLT, TA by a bioassay and PA by chemiluminescence in which neutrophils of the patient were tested with both autologous (PA1) and pooled sera from healthy subjects (PA2). We constructed a ShET-2 mutant in 2457T and tested its effect on epithelial cell invasion, plaque formation, guinea pig keratoconjunctivitis and interleukin 8 (IL-8) secretion from infected monolayers. Getting more and more complex: the pathophysiology of atopic eczema. In contrast, plasma levels of PCBs 28, 52 and 101 were significantly lower than the respective baseline concentrations, while especially notable was the significant reduction in the levels of PCDD/Fs in plasma of plant workers, which decreased from 26.7 pg I-TEQ/g lipid in the baseline survey to the current 2.5 pg I-TEQ/g lipid.

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Guidelines for the management of chronic heart failure patients can be translated efficiently into clinical practice by a specialized heart failure clinic. Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. The procedures were successfully performed in the 4 clinical cases without conversion to conventional approaches. We evaluated the use of MR cisternography after intrathecal administration of gadopentetate dimeglumine to detect the presence and localization of CSF leaks in 19 patients diagnosed with spontaneous intracranial hypotension syndrome according to the criteria of International Headache Society.

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Effect of fenbendazole on three behavioral tests in male C57BL/6N mice. Flow experience among information and communication technology users. The study subjects slept at home, and the sleep was measured with actigraphy both nights and polysomnography the last night.

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Visualization of right atrial tumor mass with transesophageal echocardiography through nasal way (TEENW). Virotherapy clinical trials for regional disease: in situ immune modulation using recombinant poxvirus vectors. Similar but less consistent correlations have been reported with cancers of the prostate, ovary, and endometrium. One hundred and seventy-two polymorphic markers were used to screen a population of 79 recombinant inbred lines (RILs) derived from the cross of Chokwang and Clark.

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Behavioural effects of tourism on oceanic common dolphins, Delphinus sp., in New Zealand: the effects of Markov analysis variations and current tour operator compliance with regulations. In this study, we demonstrat the high-throughput production of a reference peptide library using a wheat germ cell-free synthesis system to develop a large-scale SRM assay for targeted proteomics.

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In an in vivo rhesus monkey model of early pregnancy, relaxin decreases cervical collagen content, decreases cervical lumican levels, and stimulates MMP-7 levels. Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro.

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In this report, we use antibodies to map the distribution of neurons confined to selected segmental ganglia in the mud leech Haemopis marmorata. The quality of the reconstructed images was evaluated in terms of normalized mean square error (NMSE) values and two-dimensional power spectrum analysis.

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Outflow graft ligation was performed because the patient refused a pump exchange. This was associated with an increased progesterone receptor activity in the left ventricular nuclear extracts. Borrowing from the statistical thermodynamic definition of entropy, we defined a novel mathematical formula to compute the relative degree of histologic disorderliness of tumor cells. In study 3 (patient age 11 to 15 years) patients received 2, 4 and 6 mg tolterodine extended-release capsules once daily for 4 weeks each.

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A proliferation of lignocellulosic fractionation processes is arising from the need for inexpensive, homogeneous, chemically useful biomass feedstocks. Recently, motion preservation has come to the forefront of emerging technologies in spine surgery. Issues related to the use of animals in biocontainment research facilities.

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Cell walls lignified with coniferyl ferulate were more readily hydrolyzed with fibrolytic enzymes, both with and without alkaline pretreatment. The diversity of intraradicular bacterial community in teeth with apical periodontitis was higher than those without apical periodontitis.

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The purpose of this study is to provide data on the predictive validity of the Writing Sample for the national licensing exam used in the United States. Quantitative analysis of paracetamol polymorphs in powder mixtures by FT-Raman spectroscopy and PLS regression. Role of insulin resistance in predicting progression to type 1 diabetes. Rather, it is uniquely activated primarily in tumors with aberrant p53, Rb, or BRCA1 expression but not in tumors initiated through the overexpression of myc, ras, her2/neu, or polyoma middle T oncogenes. The first physician assistant program in the United States was at Duke University Medical Center.

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According to in vitro studies, integrin ligation by extracellular matrix proteins can modulate the cytotoxicity of anti-tumor agents, in a cell-type sensitive manner. Over the last 20 years, governments in Australia and elsewhere have increasingly embraced the notion of community-based treatment of the mentally ill in preference to detention in a mental health facility.

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Arabidopsis lbo mutants exhibited increased shoot branching, but the lbo mutation did not enhance the max mutant phenotype. Although other stem cells, either bone marrow derived or present within skeletal muscle or other tissues, do contribute to muscle regeneration, recent studies have highlighted that this is at best minimal compared with the ability of satellite cells to regenerate skeletal muscle. This event led to reduced contact periods between T cells and antigen-presenting cells that in turn decreased cytokine production and proliferation. This observation, which has as yet unknown laboratory and clinical significance, may be particularly useful in management of patients. The distinctive radiographic characteristics of this entity obviate unnecessary investigation and surgery.

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We sought to compare obstetric complications during labor and delivery among white non-Latina (white), black, Asian, and Latina women who delivered in California hospitals. We matched 30 patients in the early stage and 30 patients in the late stage of bipolar disorder, diagnosed according to DSM-IV criteria, with 60 healthy controls (30 matched for each group of patients). Enhanced oxidative stress (SOX) and changes in the fibrinolytic system are common in end-stage renal failure patients undergoing maintenance dialysis.

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The new MRCOG Objective Structured Clinical Examination--the examiners evaluation. Furthermore, the manipulation of chemotaxis may help to alleviate disease states, including the metastasis of cancer cells. This decrease was significant at a concentration of 10(-4) M after 12 h of treatment. A questionnaire was mailed to the 352 general practitioners working in the area covered by Grampian Health Board.

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Oral health information sheets were developed based on a review of current literature plus input from paediatric dental specialists. Immobilization of the type XIV myosin complex in Toxoplasma gondii. Malignant pleural mesothelioma appeared after one year of pleural effusion and the patient died of mesothelioma one year after diagnosis.

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Interfacial tryptophan residues: a role for the cation-pi effect? Depression in premenopausal women: gonadal hormones and serotonergic system assessed by D-fenfluramine challenge test. We conjugated biotin molecules to BSA and amine-derivatized PVA and subsequently immobilized the conjugates on epoxy-functionalized glass slides through reaction of free amine residues on BSA and PVA with surface-bound epoxy groups. Fully respecting the will of the patient at the end of her life, palliative care measures were instituted, even though the diagnosis was uncertain. To analyze the clinical value of multiple sequences derived from dual-source computed tomography (DSCT) dual-energy scan mode in detecting pancreatic adenocarcinoma.

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Esthetic and conservative restoration of the fractured incisor by means of microfilled composite materials. Some methods of obtaining quantitative structure-activity relationships for quantities of environmental interest. We retrospectively identified 126 consecutive patients who underwent laparoscopic repair of a large paraesophageal hernia between 2000 and 2010. However, gentamicin can cause drug-induced nephropathy in dehydrated patients. Compatibility of calcium and phosphate in four parenteral nutrition solutions for preterm neonates.

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Threatened extension of myocardial infarction treated by early aortocoronary bypass. Cytokines secreted by bone-metastatic breast cancer cells alter the expression pattern of f-actin and reduce focal adhesion plaques in osteoblasts through PI3K. The risk of dying by suicide is higher among men and does not increase with lower socioeconomic condition. Screening of 62 mutations in a cohort of cystic fibrosis patients from north eastern Italy: their incidence and clinical features of defined genotypes.

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Attempts to study matrilin function by gene inactivation in mouse have been frustrating and so far not yielded pronounced phenotypes, presumably because of the extensive redundancy within the family allowing compensation by one family member for another. The use of tyrosine kinase inhibitors (TKIs) has transformed the management of patients with brain metastases harboring EGFR mutations, with improved response rates (RR) and survival.

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Enzymes involved in the formation and further transformations of prostaglandin endoperoxides. During transarterial embolization, perforation of the aneurysm dome by coil and microcatheter was noted. Since OG IgG inhibits fibrinogen binding to alpha IIb beta 3, the specificity of the OG idiotype defines a novel binding motif for the integrin alpha IIb beta 3 that is shared by fibrinogen, vitronectin, and von Willebrand factor, but distinct from previously described RGD-containing sites on the fibrinogen, A alpha chain or the fibrinogen gamma chain COOH-terminal decapeptide site.

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Cerebral white matter volume may be an important variable to examine in future studies of HD. The question of how intensive motor training restores motor function after brain damage or stroke remains unresolved.

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Additionally we determined the half-life of ingested (34)SO(4)(2-) from its urinary excretion. Emerging genotypes of human respiratory syncytial virus subgroup A among patients in Japan.

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To investigate this, we used a stochastic model to study regulation of downstream target genes by a transcription factor. Thus, it is important to take this knowledge into consideration when counselling Klinefelter patients.Germ cell degeneration in the testicles of Klinefelter patients due to their additional X chromosome is an important phenomenon in this disease which is not yet fully understood. In all, 24 patients with KCS examined with slit lamp and by non-contact photomicrography.

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The evidence for self-help interventions for depressive symptoms is reviewed in the present work, with the aim of identifying promising interventions that could inform future health promotion campaigns or stimulate further research. Vanilloids in pancreatic cancer: potential for chemotherapy and pain management. The recognition that infants inheriting mutations known to cause paramyotonia congenita are inherently at risk for developing neonatal complications following an uneventful labor is important for all training neurologists so they can advise expectant mothers and pediatric and obstetric colleagues appropriately. Recent success in the treatment of chronic cough with agents used for treating neuropathic pain such as gabapentin and amitryptiline would also support this concept. This study was conducted to assess the burden of cervical cancer in India and review the performance characteristics of available cervical cancer screening tools, so as to provide evidence-based recommendations for application of most practically suited screening test to be used in resource-poor field settings.

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The TM region of CD83 blocks interleukin 10-driven, MARCH1-dependent ubiquitination and degradation of MHC class II and CD86 in DCs. Claviceps paspali, a common fungal pathogen of Paspalum grasses, attracts moth vectors by producing sugary exudates in the grass florets it infects.

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A large number of unregistered AEDs are being placed in communities. Serum uric acid is associated with microvascular function in hypertensive individuals. Test-retest and inter-rater reliability were assessed in a sub-sample of 30 patients. Overview of integrative tools and methods in assessing ecological integrity in estuarine and coastal systems worldwide. Two hundred and sixty-five hands in 152 patients were included in the final assessment.

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Cell-controlled hybrid perfusion fed-batch CHO cell process provides significant productivity improvement over conventional fed-batch cultures. The importance of this type of lesion should not be underestimated, as they often represent an early stage of a condition which could cause problems if permitted to progress. This indicated a large-scale horizontal alk gene transfer between bacteria from different subgenera. From these data it is concluded that, in healthy man, vitamin D3 is solubilised in vivo in mixed micelles only, and is governed in the aqueous phase.

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Investigating the utility of in vivo bio-impedance spectroscopy for the assessment of post-ischemic myocardial tissue. Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Our results show that mfVEP responses to stimulation of the central 5 degrees were depressed in the affected eye compared to those in the normal eye and the magnitude of response reductions was proportional to the degree of visual acuity loss in amblyopic subjects. Lessons learned from surveillance cultures in patients with acute nonlymphocytic leukemia. The percentage of IL-6-producing monocytes increased when stimulated with lipopolysaccharide (LPS) at concentrations between 10 ng/ml and 10 mug/ml, in a dose dependent manner.