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The results suggest that when the RgpA-Kgp complex, or functional binding motif or active site peptides are used as a vaccine, they induce a Th2 response that blocks function of the RgpA-Kgp complex and protects against periodontal bone loss. Metronomic irinotecan chemotherapy combined with ultrasound irradiation for a human uterine sarcoma xenograft. Determination of total N-nitroso compounds by chemical denitrosation using CuCl. The use of thiolated polymers as carrier matrix in oral peptide delivery--proof of concept.

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In general, these findings are consistent with current views on the effect of hypothalamic hormones via adenylate cyclase - cAMP system and show that the responsiveness and sensitivity of an in vitro system using whole pituitaries appears to be less that of in vivo system. The present report suggests that a careful histological examination of all ECs after surgery should be made to exclude dysplastic foci or carcinomatous transformation. These findings suggest a more optimistic view of the Internet as a source for health-related information in times of crises.

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It is tempting to speculate that NF-kappaB play a key role in the activation of cytokine in cholesteatoma. The investigators and research assistants screened both the case series and published information and data to yield relevant information. RNA of satellite nucleoli was detected in satellite as well as in characteristic nucleoli with buffered toluidine or methylene blue. Since the chemokine and its receptor, SDF-1/CXCR4, promote glioma cell proliferation and are up-regulated in human glioblastomas, we also tested the effects of VEGF on SDF-1 and CXCR4 mRNA expression.

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Five observations of hepatoblastoma in boys of 10 months to 4 years of age are presented. Knowledge, perceptions, and attitudes of Hong Kong Chinese women on screening mammography and early breast cancer management.

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In addition, the presence of a leukocyte ligand for E-selectin, sialyl-Lewis X, has been seen on cells accumulating in inflammation. High, intermediate, and low cross-reacting material-producing mutants showed similar initial rates of incorporation of labeled amino acid into alcohol dehydrogenase-like protein, presumably reflecting similar rates of synthesis.

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Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds. This study demonstrates the feasibility of using PEC micelles as a potential carrier for therapeutic siRNAs in local and systemic treatment of cancer. Melanopsin containing retinal ganglion cells are light responsive from birth. Eleven immunocompromised adults who had undergone bronchoalveolar lavage (BAL) between January 1987 and December 1996 and who had culture-verified RSV pneumonitis were evaluated.

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The model is shown to be in remarkable agreement with experiments. Fourier transform infrared (FT-IR) spectroscopy is an effective tool for investigation of chemical changes at the molecular level.

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Mechanical factors play a significant role in inducing and terminating supraventricular and ventricular arrhythmias. Simulation results show the effectiveness of the proposed system. The studies of monogenic forms of beta-cell dysfunction are no exception. Streptomycin treatment eliminated Bartonella-like bacteria in the both A. Strategies to improve dissolution and oral absorption of glimepiride tablets: solid dispersion versus micronization techniques.

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T cells that adhered to the VCAM-1-positive endothelial cells exhibited an induction in 72-kD gelatinase protein, activity, and mRNA whereas 72-kD gelatinase was not induced in the T cells that adhered to the VCAM-1-negative endothelial cells. A novel method for assessing effects of hydrostatic fluid pressure on intracellular calcium: a study with bovine articular chondrocytes. We studied sonographically the pupils and iris of 151 foetuses between 27 and 41 weeks of gestation, using maximum ultrasonic zoom. The lymphangiogenic markers PROX-1 and VEGFR3 were negatively expressed in the placenta but positively expressed in the decidua. MTT was also significantly correlated with arterial diameter and neurologic score.

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The influence of the size of the guest and the host is discussed and the effect of introducing an additional chromophore (either a phenyl or a second azo group) on the ICD spectra is demonstrated. Consequently, a variety of characterization techniques devoted to studying nanomedicine interactions with proteins and cells have been developed, since a deep characterization of nanosystems is required before starting preclinical and clinical studies. Several proteolytic activities, including that of neutrophil elastase, are reported to increase significantly in periodontal disease. Measurement by electrical impedance aggregometry of porcine platelets response to selected physiological agonists. Iontophoretic injections of PHA-L into area TE1 resulted in columnar axonal terminations in surrounding and contralateral regions of temporal neocortex and in the striatum, but not in the amygdala.

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Process data and organizational documentation were used to evaluate and monitor the experience of CORe within the organizations. EB and water content in rat brains of the pre-treated group were significantly decreased compared with the control group accompanied by reduction of MPO activity and enhancement of SOD activity. However, a total of five GST-P positive foci were detected in two out of six animals exposed to cigarrette smoke. We report a 30-year-old man with moving ear syndrome caused by focal myoclonic jerks of the right temporal muscle. Fluorescence anisotropy measurements using 1,6-diphenylhexatriene as probe molecule suggested increase of packing of the hydrocarbon chains of the amphiphiles upon addition of low concentration of urea.

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The No level in this supernatant was examined after the above-mentioned method. This article represents the update of the European Stroke Initiative Recommendations for Stroke Management. At dosages of 10 mg daily, commonly reported adverse events were somnolence, fatigue and headache. Role of insulin in the intermediary metabolism of the activated thymic-derived lymphocyte. Cyclin E was positive in seven of nine HSIL and in one of nine LSIL and in none of the ASC-US smears.

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Determination of chloramphenicol residues in shrimps by liquid chromatography-mass spectrometry. However, the deletion of p53 in BAT using a Myf5-Cre driven p53 knockout did not show any changes in body weight or the expression of thermogenic markers. We report, in two men, the occurrence of a tiny, dome-shaped, blue-gray cystic nodule of the face.

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Based on a proposed histologic definition, depth of invasion was practical for evaluating the prognosis of patients with middle and upper extrahepatic bile duct carcinomas. The proposed method provides an automatable way of measuring the appropriateness of treatment choice, which can be used for chronic diseases. Rheumatoid meningitis has not been reported to present as spells of neurologic dysfunction.

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Antibacterial and anti-biofilm activity of flavonoids and triterpenes isolated from the extracts of Ficus sansibarica Warb. Similarly, plasma NO, creatinine and blood urea nitrogen (BUN), as well as the renal immunoreactivity of iNOS and peroxynitrite, were significantly higher in heat stroke rats compared with their normothermic controls. A comparative study of their proliferative activity using proliferating cell nuclear antigen, DNA flow cytometry, and p53. Abscesses did not develop when streptococci were applied topically to swinepox lesions.

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The maximum concentration used was 990 mug/ml of freeze-dried material. The 037L gene is 1347 bp long and encodes a protein of 449 amino acids containing a biologically active RGD tri-peptide predicted with SURFC and STRIDE software. Transcriptome analysis of their hearts revealed that stanniocalcin 1 (stc1) was downregulated by sorafenib. MAP2K4/MKK4 expression in pancreatic cancer: genetic validation of immunohistochemistry and relationship to disease course.

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The clinical manifestations and cytogenetic changes of a patient with 46,XY,del(8)(p21.1) are compared with those of nine other patients with a similar deficiency of chromosome 8. Evaluation of the dose on the efficacy of the long term treatment

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These results suggest that a region of Cdc37 other than the client-binding site may be responsible for discriminating client protein kinases from others. Mutations altering synaptic connectivity between identified neurons in Drosophila. During a 12-month period, 800 pregnant women between 9 and 13 weeks of gestation, underwent first a transabdominal scan followed by a transvaginal examination, in order to compare the value of the two techniques.

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Molecular genetic studies are, however, still few and preliminary. The use of pelvic radiation therapy as shown by the Gynecologic Oncology Group (GOG)-99 trial improves the event free interval at the cost of increased toxicity. Under voltage clamp, an inward current was recorded at similar times, with reversal at about -15 mV. Effects of intermittent hypoxia on pulmonary haemodynamics: animal models versus studies in humans.

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In vitro studies were carried out in oxidized LDL (oxLDL)-stimulated HUVECs treated with or without CTS. Aqueous-plasma and vitreous-plasma ratios of fluorescein isothiocyanate-dextran (70,000 molecular weight) after intravenous administration were less than 0.004 in detached and fellow eyes.

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The combination of tenofovir and didanosine results in an increase in the didanosine plasma exposure and might augment the risk for didanosine toxicity. Changing patients to the oral osmotic system with hydromorphone at a ratio of 1:5 morphine equivalents usually led to good analgesia in one or two titration steps. To our knowledge, this is the second case reported of SFT originating from the tongue. Ruthenium catalyzed decarbonylative arylation at sp3 carbon centers in pyrrolidine and piperidine heterocycles.

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In addition to previously identified components of GLUT4 storage vesicles including the insulin-regulated aminopeptidase insulin-regulated aminopeptidase and the vesicle soluble N-ethylmaleimide factor attachment protein (v-SNARE) VAMP2, we have identified three new Rab proteins, Rab10, Rab11, and Rab14, on GLUT4 vesicles. Buccal and oral application produced more prolonged TSH and PRL increases, achieving plateau levels after 120 min to 180 min. Haplotype AH2 was found in four tortoises from the border territory between Uzbekistan, Tajikistan, and Afghanistan.

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Environmental noise-exposed workers: event-related potentials, neuropsychological and mood assessment. The questionnaire measures smoking status, gender, social, and cultural aspects as well as predictors of smoking.

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The pharmacogenetics of morphine-induced analgesia: a case report. Spectral sensitivity of the concave mirror eyes of scallops: potential influences of habitat, self-screening and longitudinal chromatic aberration. Tramadol, a synthetic opioid that acts at multiple sites, is considered to be an effective treatment for PAS, but the evidence for its therapeutic benefit after remifentanil anesthesia is limited. Supplementing lactating women with flaxseed oil does not increase docosahexaenoic acid in their milk. Cell-mediated lysis of lipid vesicles containing eye muscle protein: implications regarding pathogenesis of Graves ophthalmopathy.

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We even could observe in some parameters a difference favoring group one having a normal EEG compared to group two with only slightly impaired EEG-patterns. Biomechanical studies of the stability of the cervical spine in the NIH, currently underway, will help to assess the suitability of the NIH as an alternative to CHs. Aortic bypass and orthotopic right renal autotransplantation for midaortic syndrome: a case report. To describe self-reported oral health status before and after treatment in patients treated with fixed, removable, and complete dentures. The primary investigator evaluated each patient and determined a hospital behavior score, anesthesia recovery score, preoperative pain score, and serial postoperative pain and sedation scores over 38 hours.

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Antimutagenicity and DT-diaphorase inducing activity of Gynostemma pentaphyllum Makino extract. In this study, state-level US data for the years 2000 and 1990 are used to provide additional evidence on the roles of income inequality and poverty in population health. First, issues arising from international literature, including factors relating to access, equality and workforce issues, care satisfaction and placement decision-making. Patient demographics, indications for surgery, preoperative and postoperative International Prostate Symptom Score, uroflowmetry scores, operative time, catheterization duration, hospital stay and complication rates were compared.

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Effect of the leukotriene receptor antagonist montelukast therapy on asthma in childhood By implementing the DNA hydrogel to induce an impedimetric response change, this impedimetric biosensor exhibited an excellent analytical performance towards the HPA quantitative assay, with a low detection limit of 0.003 pg mL-1. Monoclonal antibodies (mAbs) against growth factors, receptors and tumor-specific/tumor-selective antigens represent a rapidly growing class of pharmaceutical agents which are poised to make a major impact on the treatment of colorectal cancer. Vibrio parahaemolyticus and Staphylococcus aureus were sensitive to many kinds of plant extracts, whereas Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella Enteritidis populations decreased in only six, one, and three plant extracts, respectively. Several laboratories have shown that methamphetamine (METH) neurotoxicity is associated with increases of nitric oxide (NO) production in striatal tissue and blockade of NO production protects from METH.

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In spite of the large differences in pH and/or viscosity between the bulk and interface, the unchanged equilibrium between the two molecular forms on varying the medium pH or viscosity provides a huge advantage for the exclusive detection of interfacial polarity. To assess the efficacy of zaleplon 10 mg and zolpidem 10 mg administered during experimental middle-of-the-night awakenings in patients with sleep-maintenance insomnia using objective polysomnographic measures and to assess daytime residual sedation 4 to 7 hours after dosing using sleep-latency testing. However, there has been no complete study relating the lubrication efficacy of magnesium stearate to various levels of solid state.

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From the third round of the Community Tracking Study, Physician Survey, 2000-2001. FLIP was constitutively expressed in cultured neonatal rat cardiac myocytes.

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IPAH cells had greater migration than control cells but less organized tube formation in in vitro angiogenesis assay. In general, the highest outdoor and indoor hourly concentrations were observed from 10:00 to 15:00 h. Furthermore, washing peritoneal cytology histologically revealed the presence of carcinoma cells. We propose guidelines for use of a novel microwave ablation system and recommend use at 45 W for 10 min. Thymoma, a tumor of thymus gland, is of epithelial origin and is most common anterior mediastinal tumor.

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In consequence, our studies demonstrate that the cytokine-induced rapid immune adaptation of the proteasome system is a tightly regulated and transient response allowing cells to return rapidly to a normal situation once immunoproteasome function is no longer required. We performed molecular dynamics simulations of the electrostatic assembly of multilayers of flexible polyelectrolytes at a charged surface. Results from in vivo of intraperitoneal injection and in vitro static cultures showed that estradiol increased the mRNA expression of PSS1 gene in both hypothalamus and ovary. Subjects were 12 patients with an ICD (10 men, 2 women) and 4 partners (1 man, 3 women). When assessed as a categorical variable, LNR was the most powerful manner to stratify patients on the basis of LN status.

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HepK and HepN also affected transcription of a common set of genes and therefore appear to share a regulatory pathway. Role of transglutaminase 2 in apoptosis induced by hydrogen peroxide in human chondrocytes. After initial resuscitative measures, the patient received on-site hyperbaric oxygen therapy and demonstrated no residual clinical sequelae from this complication.

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Etoricoxib demonstrated a significantly high rate of occurrence and completeness of its analgesic effect. The detection efficiency and the pulse-height distribution have been determined for a homogeneous contamination of 241Am in bone. DNA sequencing validation of Chlamydia trachomatis and Neisseria gonorrhoeae nucleic acid tests. An efficient method for the synthesis of enol ethers and enecarbamates.

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Far bias on the radial line bisection task: measuring perceptual-attentional and motor-intentional bias in normal subjects. The natural evolution of the hyperdense component of temporal lobe lesions was to enlarge within the first few hours after the injury. Unusual extensive granulomatosis after long-term use of plastic syringes for insulin injections.

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Cholesterolosis is the most frequent cause of polypous space-occupying growths of the gall bladder. A simple disk-diffusion test for differentiation of yeast species. The highest averages of TDPb in the petroleum and coal basins in the Western Harbor reflect their effects on the water column, while the lowest averages of TDPb and TPPb were found at a location far away from pollution sources.

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Standardised photographs of the palate and microbial samples of palate, upper and lower dentures were taken before and after treatment. Our study emphasizes the need for better understanding of long-term safety and efficacy of maintaining supraphysiologic levels of IGF-Iz.

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However, long-term results of isolated LSG performed in patients with lower body mass index (BMI) (30-35 kg/m(2)) are scarce. This integrated systematic exploration of RNA targets for homologous RNA-binding proteins indicates an unexpectedly high conservation of the RNA-binding properties and of potential targets, thus predicting conserved RNA regulons. A 34-year-old oligophrenic woman was admitted in comatose state with marked tachypnea. Reduction of beta-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated beta-catenin. Comparison of idiopathic, post-trauma and post-surgery frozen shoulder after manipulation under anesthesia.