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He had complex partial seizures refractory to several antiepileptic drugs since 4 years of age. In conclusion, ET-1, in contrast to selective ETA antagonist, exerts some protective effect in the early course of oedematous cerulein-induced acute pancreatitis in rats. A recent quantitative electron microscopic study of biopsy samples of the cerebral cortex of neurologically normal individuals, aged between 15 and 54 years, has shown that atypical inclusions are present in neuronal and glial processes in small but appreciable numbers (Rees). Despite this marked difference in both the rate and extent of zinc MT accumulation there was little evidence of a difference in the rate of MT synthesis. Four members of the twist gene family (twist1a, 1b, 2, and 3) are found in the zebrafish, and they are thought to have arisen through three rounds of gene duplication, two of which occurred prior to the tetrapod-fish split.

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Injection of Staphylococcus aureus EDIN by the Bacillus anthracis protective antigen machinery induces vascular permeability. Allergies, infections and the hygiene hypothesis--the epidemiological evidence. Coexisting conditions (e.g., anxiety, learning, mood, or sleep disorders) should be identified and treated. Pregnancy in a Patient With a Malignant Brain Tumor Taking Temozolomide: Case Report and Review of the Literature.

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Virulent mycobacterial strains elicit much less apoptosis than attenuated strains, implying that apoptosis is a defense against intracellular infection. Safety and Utility of Quantitative Sensory Testing among Adults with Sickle Cell Disease: Indicators of Neuropathic Pain?

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In-situ measurements of chondrocyte deformation under transient loading. It is concluded that exposure therapy is a form of cognitive intervention that specifically changes the expectancy of harm.

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RNase-induced apoptosis was associated with activation of initiation caspase-8 and -9. One type is a necklace of oblate subunits with two circular domains of the liquid-order phase, and the other is a periodically modulated tube with stripes of the liquid-order phase.

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This report describes the echocardiographic diagnosis of right atrial thromboembolism with histopathological validation after successful surgical removal. The results showed that a minimum of about 2.7 x 10(3) enveloped virus particles/cell were required for an optimum visualization of EBV binding to the target cells tested, and that a lymphoid cell may bear receptors for one prototype strain of EBV but not for the other. Interstitial leukocyte trafficking is the result of amoeboid polarization and migration, guided by soluble or tissue-bound chemoattractant signals for positioning and local arrest. A combination of gestalt therapy, Rosen Body Work, and Cranio Sacral therapy did not help in chronic whiplash-associated disorders (WAD)--results of a randomized clinical trial.

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Thyroid hormone has long been known to have important transcriptional regulatory activities. Carbofuran was detected in the stomach contents by gas chromatograph-mass spectrometry. This technology can be used to measure emission fluxes from tailings ponds with better detection of spatial and temporal variations of fugitive emissions. This activity of the cultured cells requires the presence of BRBC both during the in vitro incubation and in the footpad.

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ATP-induced osteoclast function: the formation of sealing-zone like structure and the secretion of lytic granules via microtubule-deacetylation under the control of Syk. It has been hypothesized that either increased apoptosis of intestinal epithelium or decreased apoptosis of lamina propria lymphocytes may induce inflammation of gut. On the other hand, HMG did not change TBA-RS levels in intact or disrupted mitochondrial preparations, indicating that generation of oxidants by this organic acid was dependent on cytosolic mechanisms. Here, we investigated whether polymers can act as adjuvants to increase the in vivo efficiency of AAV2. Weight loss programs for urban-based, postpartum African-American women: perceived barriers and preferred components.

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Their rheological behavior is largely governed by the contour length of the micelles and the concomitant propensity of the micelles to overlap and entangle. The deleterious biological effects of low-level, long-term exposure to heavy metals are well known, and children are the most susceptible population. Improving upper limb function is a core element of stroke rehabilitation needed to maximise patient outcomes and reduce disability.

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For real data, however, we typically find that the classification performance of phylogenetic footprinting surprisingly increases with increasing substitution probabilities and is often highest for unrealistically high substitution probabilities close to one. The effects of 5-hydroxy-6-methyl-2-aminotetralins were evaluated for central and presynaptic peripheral dopaminergic activity. NO in macrophages is generated via the inducible nitric oxide synthases (iNOS). In particular the WBCR method accurately finds the anisotropic propagation early after epicardial pacing, and the WBPR method finds the wavefront (regions of sharp gradient of the potential) both accurately and with minimal smoothing. The sequoiamonascins were isolated by brine shrimp lethality-guided fractionation and were submitted to the NCI for anticancer evaluation.

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Visual acuity, refraction, keratometric readings, and slit-lamp biomicroscopy findings at 1, 3, and 6 months postoperatively. Factor VIII related antigen in term and preterm newborns with severe neonatal haemorrhage. This article considers the evidence for an imitative deficit in autism and for the possible role of deficiencies in the representation of actions. The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?

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24 hr prior to drug administration, indicating that the effect was produced through activation of peripheral alpha-adrenoceptors. High-throughput method for N-terminal sequencing of proteins by MALDI mass spectrometry.

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To describe the incidence of outcomes during and after the periprocedural period among Medicare beneficiaries undergoing CAS. Clinical significance of spontaneous Aeromonas bacterial peritonitis in cirrhotic patients: a matched case-control study. Shortly before this explosion in functional connectivity research, developmental neuroscientists had proposed theories based on neural systems models to explain behavioral changes, particularly in adolescence. Doppler ultrasonographic evaluation of ductus venosus blood flow in 55 canine fetuses. Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state.

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An uncovered expandable metallic stent was inserted into the stenotic region. Promotion of physical activity for secondary prevention in patients with chronic diseases: the situation in the Grand-Duchy of Luxembourg Similarly to DOPAC, haloperidol had a pronounced retarding effect on the efflux of homovanillic acid (HVA) from the brain. This receptor represents a heterogeneously glycosylated transmembrane protein that binds both IgA subclasses with low affinity. The prepared HRP/TTF-TCNQ/MWCNTs/Au electrode was used for the bioelectrocatalytic reduction of H(2)O(2), with a linear range from 0.005 to 1.05 mM and a detection limit of 0.5 microM for amperometric sensing of H(2)O(2).

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The main advantages of the above two methods in routine diagnosis are discussed. Relevance of conventional radiography in indicating maxillary antral lavage. Impression technics for the prosthetic treatment of Kennedy Class I edentulousness in the mandible An evaluation of stanolone in treatment of advanced mammary cancer.

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There are several versions of the Diagnosis Related Group (DRG) classification systems that are used for case-mix analysis, utilization review, prospective payment, and planning applications. Insomnia is a sleep disorder in which the subject encounters problems in sleeping. With this filtering, the P300 component is accurately localized in both time and scale. Despite equal bindings of polycations at 4 degrees C and 37 degrees C, significant leak occurred only at 37 degrees C, suggesting the role of active processes in the maintenance of permselectivity. Analysis of polypeptide composition and antigenic components of Rickettsia tsutsugamushi by polyacrylamide gel electrophoresis and immunoblotting.

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Further studies incorporating dexamethasone to 5-HT(3) antagonists will be necessary to determine the relative efficacy of palonosetron compared with available agents. Concentrations of PG, ET-1, and Ang II in 4-h fractions were measured using second-antibody enzyme immunoassays. This process does not persist beyond the early elongation phase. Insufficient treatment associated with recurrent ulceration and altered anatomy.

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Substitution of threonine 159 with the nonphosphorylatable residue alanine markedly diminished activation of the cardiac alpha-actin promoter in the presence of kinase, while its substitution with aspartic acid, to introduce a negative charge and mimic phosphorylation, restored activation completely. The available common cold remedies are of limited utility and specific antiviral approaches have been unsuccessful. FK778 is a synthetic malononitrilamide (MNA) that has been demonstrated to have both both immunosuppressive and anti-proliferative activities. Intraoperative microrecording revealed a significant correlation between neuronal activity of the ventral intermediate nucleus (Vim) and tremor electromyograms.

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Aberrant CDKN1A transcriptional response associates with abnormal sensitivity to radiation treatment. The frequency of formation of the Probst bundle was highest for axons from frontal cortex, which arrived at midplane first, and lowest for occipital axons, which arrived last. The numerous causes of fertility impairment outside the endocrinological field (internal medical and urological diseases, consumption behavior, psychic disturbances, medicines etc) are referred to. Syngeneic anti-(anti-Id) antibodies were prepared against BALB/c anti-A48Id antibodies, BALB/c anti-460Id monoclonal antibodies, and A/J anti-J558 IdI monoclonal antibodies.

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An emergency department guideline for the diagnosis of pulmonary embolism: an outcome study. A novel nonsense mutation and polymorphisms in the mouse hairless gene.

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These results show that ET-3 applied to the brain modified through a nitric oxide pathway distinct bile flow fractions depending on the administered dose and give further insights into the complexity of brain-liver interaction. However, little is known concerning the relationship between DPD expression and clinical malignant potential, especially in urological cancer. Moreover, EP4 signaling induced expression of amphiregulin and epiregulin in activated macrophages, whereas EP4 pathway was required for basal expression of epiregulin in gastric epithelial cells. k-space methods are well suited to modeling high-frequency acoustics applications as they require fewer mesh points per wavelength than conventional finite element and finite difference models, and larger time steps can be taken without a loss of stability or accuracy. Hepatocellular enzyme patterns and hepatitis B virus exposure in multitransfused young and very young hemophilia patients.

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It has been reported that complete caries removal from cavities during restoration of teeth is difficult. To assess dose effect relationship between inhaled corticosteroid, the Finney parallel line bioassay is the reference method with a study period of at least 6 weeks. Several studies have demonstrated some benefits of the use of growth factors in experimental models of ARF. The probing depth was slightly greater in the control group as was the gain in clinical attachment, but neither was statistically significant. Los datos indican que la BNB en la esclerosis multiple es una herramienta sensible para identificar alteraciones cognitivas en la esclerosis multiple, con especial enfasis en las tareas de memoria de trabajo.

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Million women study report on ovarian cancer meets more criticism. Inherent differences between ML, a number-based measure, and MRT, a mass-based measure, and the inability of the MRT method to account for multiple replacements of rapidly cycling roots were the two sources of error that contributed more to the disparity than did the improper choice of root age distribution models and sampling bias. Cirrhosis is associated with a higher mortality, a longer time of ICU and hospital stay of trauma patients. All patients with HIV and diagnosed R equi infection until September 1998. Expression and modulation of adhesion molecules on human bronchial epithelial cells.

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In vitro and in vivo degradation of biomimetic octacalcium phosphate and carbonate apatite coatings on titanium implants. Cross protection in mice with the Smith diffuse stain of Staphylococcus aureus versus a type Ia strain of group B streptococci. We used a data-driven modeling approach to generate a model that instead uses recurrent network dynamics with a single, fixed temporal integration window to implement the velocity computation. There was no evidence of detrimental effects of maternal employment in the early years on subsequent child socio-emotional behaviour. Carvedilol was added on ACEI, diuretics and digitalis regimen for a target dose of 50 mg/d.

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(Coleoptera: Meloidae) is a traditional medicinal insect recorded in the Chinese Pharmacopoeia. These data suggest that cilia are intrinsically involved in PCP processes. Bone marrow-derived MSCs were obtained from 10 DM patients (5 type 1 DM and 5 type 2 DM) and induced to IPCs under a three-stage protocol.

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Effect of Lactobacillus acidophilus on starter pigs fed a diet supplemented with lactose. The informant gives an account of the situation of tuberculosis in India (Epidemiology, Tuberculosis Control). A clinical risk index for Clostridium difficile infection in hospitalised patients receiving broad-spectrum antibiotics. The proportions of each class reported by participants depended on contrast. The factors that may have contributed to the genesis of the immune imbalances we have detected are discussed.

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The binding site of TGG-II-23A appears to be in close proximity to that of the TIBO-like inhibitors, since a TIBO-resistant HIV-1 was also resistant to TGG-II-23A treatment. The transverse diameter may be useful in estimating fetal age, particularly in breech presentation where extrinsic pressure may deform the skull and decrease the biparietal diameter. Richness was consistently lowest in the deepest soil horizon samples.

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Caco-2, human colon carcinoma cell line, has been widely used as a model system for intestinal epithelial permeability because Caco-2 cells express tight-junctions, microvilli, and a number of enzymes and transporters characteristic of enterocytes. The aim of this study was to use numerical methods to compare the biomechanical effect of treating proximal humeral fracture. Raman spectroscopic study of space structure of membrane proteins and membrane lipids in photodamaged human erythrocyte sensitized by hypocrellin B.

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Comparison of the antiemetic efficacy of two high-dose benzamides, metoclopramide and alizapride, against cisplatin-induced emesis. These forehead flaps were alive in all patients, all incision healed in I stage, no post operative complications were found. Studies were repeated after 6 months of therapy with parenteral vitamin D2 (100,000 IU i.m.

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Alcohol-induced hypertension--just how much of a cardiovascular risk factor? Combining nonlinear dimensionality reduction with wavelet network to solve EEG inverse problem.

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Phosphorylated Ugp1 is required for intensive glucan production, and inability to phosphorylate Ugp1 is associated with a weak cell wall, decreased glucan content, and increased glycogen content. In 2001, recombinant human activated protein C was shown to improve survival in patients with severe sepsis, but two further studies of the immunomodulatory effects of endogenous anticoagulant agents did not show any survival benefit. These results clearly proved inhibitory effects of nimbolide on tumour cell invasion and migration by down-regulating proteins critically involved in regulation of cell invasion and metastasis, suggesting a possible therapeutic role of nimbolide for breast cancer.

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Identification of the serum lytic system homologous to mammalian complement. Current motion correction methods make restrictive assumptions on the type of motions, for example, that it is a translation or rotation, and use special properties of k-space for these transformations. In this study, we investigated the role of FBXO6 in cadmium-induced ER stress in HEK293 cells. Computerized ICP monitoring can benefit the assessment of shunt function, and can accurately characterize the status of CSF compensation in shunted children with a complex presentation. Multi-element analysis of South African wines by ICP-MS and their classification according to geographical origin.

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In the first round, the experts reviewed the LEI and completed a questionnaire. Choriocarcinoma is so rare and presents such different pictures that its diagnosis may be delayed or missed entirely, depriving the patient of early treatment and the chance of a cure. 103P: Lobectomy for non-small cell lung cancer in octogenarians: A 7-year single center experience. However, a subset of patients is either refractory to first-line treatment or develops recurrent disease after an initial remission.