Kofron is a semisynthetic macrolide antibiotic, structurally very similar to erythromycin. It inhibits protein synthesis by penetrating the cell wall and binding to the 50S ribosomal subunit. The absolute bioavailability of Kofron after oral administration is 50-55%, which probably underestimates its systemic activity, as it undergoes extensive first pass metabolism to its active metabolite, 14-hydroxyKofron. Limited data are available on the distribution of Kofron in humans. It appears to be distributed into most body tissues and fluids. However, no data is available on CSF penetration of Kofron. Elimination of Kofron follows nonlinear kinetics. It is extensively metabolized in the liver and excreted as parent drug and metabolites in urine, and faeces.
Other names for this medication:
Clarithromycin,
Biaxin,
Abbotic,
Aeroxina,
Biclar,
Binoclar,
Bremon,
Clabel,
Clamycin,
Clarimac,
Clarimax,
Clarimed,
Clarimycin,
Claripen,
Claritt,
Clariva,
Clariwin,
Clarix,
Claromycin,
Claron,
Cleron,
Emimycin,
Euromicina,
Finasept,
Fromilid,
Infex,
Kailasa,
Kalixocin,
Klabax,
Klabet,
Klabion,
Klarimac,
Klarimax,
Klarithran,
Klax,
Klaz,
Klerimed,
Kofron,
Krobicin,
Lekoklar,
Macladin,
Maclar,
Macrobid,
Macrol,
Monozeclar,
Naxy,
Synclar,
Taclar,
Veclam,
Vikrol,
Xylar,
Zeclar,
Zeclaren,
Similar Products:
Grenis,
Prostol,
Trichozole,
Fladystin,
Metroson,
Cefirax,
Activir,
Prosogan,
Aluron,
Verisan,
Ciprofloxacina,
Vanadyl,
Filibuvir,
Tolbin,
Imadrax,
Benoxil,
Gabaran,
Omexel,
Apazol,
Rimox,
Baclofene,
Metrolyl,
Tegretol,
Flamus,
Actrim,
Vilitra,
Lucen,
Paxyl,
Osyrol,
Levoxacin,
Forcid,
Acipan,
Rofex,
Fenixa,
Tetracon,
Acitop,
Pidocar,
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