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Alkylating agents are a significant class of environmental carcinogens as well as commonly used anticancer therapeutics. Baseline GH and age were significant covariates for the clearance. Fractionation of mercury in sediments from coastal zone inundated by tsunami and in freshwater sediments from the rivers. Previous studies have revealed that anesthesiologists are generally unaware of drug costs. The added value of ECG-gating for the diagnosis of myocardial infarction using myocardial perfusion scintigraphy and artificial neural networks.

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Six female healthy volunteers (age range, 20-46 y) and 6 female patients (age range, 23-42 y) were enrolled in this study. A Japanese population was typed for HLA-D antigens for the first time using HLA-D homozygous typing cells Dw1 through Dw4 and the homozygous cells LD HO and LD AH, newly found in the Japanese population. These preparations are part of a natural health care system from India, known as Maharishi Ayur-Veda. The expression of this gene was not detected in the enteric smooth muscle cells or, unlike its avian and mammalian homologues, in the somites/skeletal muscle of the Xenopus embryos/tadpoles. The present study was designed to test the null hypothesis that there is no difference in the fracture resistance of pulpless teeth restored with different types of post-core systems and full coverage crowns.

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The objective of this study is to assess the awareness and practices of complementary and alternative medicine (CAM) for oral health-care management among dental students. However, cilia surrounded by a plasma membrane were regularly present. This is the first report of the cardioembolic stroke due to simultaneous occlusion of the three major arteries to the brain. Parallel identification of proteins from complex mixtures down to low-femtomole levels makes nano-HPLC/nano-ESI-FTICRMS an attractive approach for proteome analysis.

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Cancer stem cells (CSCs) are thought to be responsible for tumor regeneration after chemotherapy, although direct confirmation of this remains forthcoming. We review MR imaging of the prostate and its use in targeted therapy, and describe our use of image processing methods such as image registration to further facilitate precise targeting. Is the renal natriuretic peptide urodilatin involved in the regulation of natriuresis?

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Our studies show that, in addition to TNF-mediated signaling, TNF-independent signaling induced by I/R injury can contribute to the activation of the HCMV enhancer. Effect of soil properties and aging on the toxicity of copper for Enchytraeus albidus, Enchytraeus luxuriosus, and Folsomia candida. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. In both the daily and semiweekly poly ICLC regimens, hamsters receiving bleomycin plus poly ICLC demonstrated increased mortality and decreased weight gain compared to the vehicle and bleomycin control groups.

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Precueing time but not direction of postural perturbation induces early muscular activation: comparison between young and elderly individuals. Effect of auranofin dose regimen change upon cell-associated gold in rheumatoid arthritic patients. The pipelle is a safe device for getting an adequate endometrial sample for histology, with a high sensitivity and specificity for detection of hyperplasia and malignancy. Established permanent AF was examined in relation to primary clinical, echocardiographic, and electrophysiological parameters. We identified SET-2, the homologue of yeast and mammalian SET1, as an antagonist of HPL-1 and HPL-2 activity in growth and somatic gonad development.

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Coronary angiography was performed in 20 patients on the seventh postoperative day when the grafts were patent. The abdomen was vascularly isolated, perfused through the aorta at constant flow and drained through the inferior vena cava at constant pressure.

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Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Recently, dental follicle cells (DFCs) from retained human third molars have been isolated and characterized as osteogenic progenitors. Dye-sensitized photosynthesis: Eosin Y (EY), a dye photosensitizer, works efficiently as a molecular photoelectrode by catalyzing the visible-light-driven electron-transfer reaction for efficient regeneration of NADH through a photosensitizer-electron relay dyad.

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The aim of this technical analysis and the juxtaposed discussions is to elucidate with the most important milestones and technical tips and tricks all aspects of a feasible and reliable RYHJ technique that is performed in our center for the last 25 years in around 400 patients. Skull base surgery program of the Republic of Cuba: establishing a demanding subspecialty in a developing country. Results suggest that the ridle is advantageous when mandatory covariates are correlated with the irrelevant optional predictors or are highly correlated among themselves. Baseline samples were used to evaluate basal hormonal, metabolic and lipid levels.

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Mapping of perineuronal nets in the rat brain stained by colloidal iron hydroxide histochemistry and lectin cytochemistry. The development of all four transformation characteristics as a result of introduction of the src gene, and their coordinate reversal by cAMP derivatives, supports the previous thesis that in the normal vole or CHO fibroblast all four properties are part of a common regulatory system. Since human aging has been associated with a deterioration of the gut microbiota (GM)-host mutualism, here we investigated the composition of GM in DS.

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Twenty-six patients were treated for duodenal or recurrent ulcer with selective gastric vagotomy plus precise antrectomy--that is, complete removal of the entire antrum. To fill the family health history practice gap, Cleveland Clinic has developed a family health history collection and clinical decision support tool, MyFamily. These data suggest that pain is an important predictor of depression in elderly primary care patients. Contrast-discrimination performance was assessed with the steady-pedestal (magnocellular) and pulsed-pedestal (parvocellular) stimuli of Pokorny and Smith for seven pedestal luminances between 15 and 60 cd/m(2) on a background of 30 cd/m(2). Consistent with the complement-regulatory ability, the inhibitory effect of the deposition of C3 fragments by these molecules was closely related to the degree of amelioration.

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Laparoscopic splenopexy for wandering spleen: extraperitoneal pocket splenopexy. The condition of manatee carcasses submitted for routine postmortem examination was categorized as fresh, moderately autolyzed, or severely autolyzed. Removal of blood contamination from fine needle aspiration cytology sample using a gauze swab. Minocycline also attenuated morphine conditioned place preference.

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In chronic hepatitis B, several pretreatment parameters have been identified for prediction of virologic response to interferon alfa-based antiviral therapies or treatment with polymerase inhibitors. The production capacity of the peripheral blood monocytes was not similar to that of the peritoneal Mvarphi.

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We have assessed several age-sensitive indicators of immune status in young (i.e., 6 to 11-month-old) mice of a genetically heterogeneous population to see if these varied in parallel and to determine if one or more of the status indices predicted life span or cancer incidence. The results of such trials will decide about the future of new drugs and are the basis of evidence-based medicine and the development of clinical guidelines.

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Invasive breast cancer cases were retrieved from the National Breast Cancer Audit database for the 274 participating breast surgeons in Australia and New Zealand. As bifidobacterial fragments in PCR/DGGE profiles generated from microbiota DNA showed increased intensity of fragment staining, an increase in bifidobacterial numbers in colitic mice was indicated.

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The result is consistent with the current biochemical and structural findings that the C-terminal helix of apo C-II is important for activation of LPL. The expression of the mouse mammary tumor virus (MMTV) in hormone-induced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27.

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These findings support our hypothesis that altered EC function contributes to the pathophysiological aspects of suicidal behavior. Antimutagenic and anti-oxidant activities of the non-steroidal anti-inflammatory drug celecoxib.

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Adenoviral vectors used in gene therapy are predominantly derived from adenovirus serotype 5 (Ad5), which infects a broad range of cells. The simulation results are used to suggest in vitro experiments to test the conformational transitions involved in the maturation of plasmepsin, and design small-molecule inhibitors. To investigate relationships between anxiety and stressors,coping and subjective burden and to contribute to defining factors related to anxiety among family caregivers of older dependents.

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Results showed an increased motor excitability for the rehearsed but not for the non-rehearsed piece. Thirteen healthy females and thirteen untreated patients with carcinoma of the uterine cervix were studied for spontaneous and mitomycin C (MMC)-induced rates of sister chromatid exchange (SCE) and cell cycle progression. The epitope was sensitive to treatment with SDS and was dependent on the formation of a disulfide bridge. In order to achieve high sensitivity and selective detection for aromatic compounds, cyclodextrin (CD) hosts and imprinting effects were combined to fabricate binding sites within TiO(2) ultrathin layer.

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Dose-response investigations revealed very low response thresholds to the tested compounds. In this study, 8 patients with PRES were reviewed, retrospectively. The disease is characterized by brachydactyly type E, short stature, arterial hypertension and aberrant loop of posterior inferior cerebellar artery (PICA) causing neurovascular conflict.

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Back pain is one of the most common and expensive health problems in Germany. The titanium bone growth chamber consists of two titanium disks held together by two screws.

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period (1970-1990), (2) urbanization was negatively associated with male suicide mortality rates in most of the age classes in the 1980s, (3) unemployment was one of the major determinants of increased suicide mortality rate in middle-age men in the 1980s, and (4) unemployment was the major factor which was inversely associated with suicide mortality rate for elderly women from 1980 to 1990 in Japan. Effects of denervation on the rate of entry of inorganic phosphate into rat slow and fast muscles: selective inhibition of denervation changes by actinomycin D. Coronary heart disease associated with the use of highly active antiretroviral therapy (HAART). Local delivery of TGF-beta/BMP ligands is commonly used as a tissue engineering strategy for the spatial regulation of cell growth and differentiation. Cubic chemically ordered FeRh and FeCo nanomagnets prepared by mass-selected low-energy cluster-beam deposition: a comparative study.

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Electron microscopic examination of exocrine pancreatic tissues from the fish Scorpaena scrofa L., probably captured while replenishing the acinar cells, shows two main functional cell morphologies of the same cell type. The results suggest that CIC detected by the C1q-BT do not bear C1q in significant amounts in the circulation and that these CIC become detectable only in the presence of PEG. In this report, we used ten different recombinant DBL-alpha fusion proteins expressed in Escherichia coli to generate antibodies in experimental animals. Fine-needle aspiration (FNA) of the thyroid gland has proven to be an important and widely accepted, cost-effective, simple, safe, and accurate method triaging patients with thyroid nodules.

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A new caval tree system was designed for realistic in vitro simulation. We evaluated the relative influences of noncritical lower limb arterial disease and peripheral neuropathy on cutaneous foot perfusion in diabetes. Insect elicitors and exposure to green leafy volatiles differentially upregulate major octadecanoids and transcripts of 12-oxo phytodienoic acid reductases in Zea mays. The hi472 mutant larvae in fact suffered from a severe loss of functional neuromasts of the lateral line mechanosensory system, a reduction of zVIPL labeling in support cells, and a reduction or even a complete loss of hair cells in neuromasts. Schizosaccharomyces pombe contains seven JmjC proteins, but it was unclear whether any of them functioned as histone demethylases.

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Coverage targets and equity targets for all primary health-care services, including immunization of children, were explicitly included in the contracts awarded in five of nine rural districts which together have a population of over 1.25 million people. Both physicians and nurses play important roles in discussing do not resuscitate (DNR) orders with patients and surrogates.

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The importance of this new disease is characterised by the growing number of patients. We show here that recombinant hBACAT also can hydrolyze long- and very long-chain saturated acyl-CoAs (mainly C16:0-C26:0) and by mass spectrometry verified that hBACAT also conjugates fatty acids to glycine.

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Employing a more holistic approach, including urological therapy, physical therapy, and psychosocial perspectives, may be more appropriate for most patients. Anesthesia for foreign bodies in the tracheo-bronchial tree in children.

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In susceptible NAN families, the risk of RA was reduced by IL-10 genotypes, whereas the SE did not affect risk. The binding of human endothelin B receptor to its natural peptide ligand endothelin-1 is demonstrated by coelution, pull-down assays, and surface plasmon resonance assays. Adenylate cyclase (AC) activity was also determined in FV-P spleen membrane preparations in response to albuterol and PGE1. RAPD analysis with four primers was used to examine the genetic relationship among 432 strains of Listeria monocytogenes isolated from clinical and veterinarian cases of listeriosis, dairy, vegetable, meat- and fish-based food items, environmental samples and samples collected from one transport terminal, one poultry-processing company and four Atlantic salmon-processing plants. Scleral material properties were fit to each eye using a microstructure-based constitutive formulation that incorporates the collagen fibril crimp and the local anisotropic collagen architecture.

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This increase was followed by the accelerated recovery of all the mature blood cell lineages. Evaluation of variations and affecting factors of eco-environmental quality during urbanization.

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Further experiments confirmed that performance on the associative test was not influenced by testing order (Experiment 3). The recommended vaccines and vaccine schedule are discussed in detail. Differences in passive electrical resistance of electronically linked dual pathways within the AV node may account for functional longitudinal dissociation, reentrant arrhythmias, and responses to catheter ablation therapy.

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A total of 924 articles were obtained, but 27 were included in the analyses. Seventeen patients were identified who had placement of an intracranial pressure monitor and reamed rodding of the femur. This antibody would be of great use for studying the divalent cation-dependent modulation of the integrin molecules and bring another aspect to the understanding of the regulatory mechanisms of ligand binding of the integrin molecules. The Sharpshooter Genus Geitogonalia Young: Descriptions of a New Brazilian Species and of the Female of Geitogonalia quatuordecimmaculata (Taschenberg) (Hemiptera: Cicadellidae). Kazinol C from Broussonetia kazinoki activates AMP-activated protein kinase to induce antitumorigenic effects in HT-29 colon cancer cells.

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The most striking effects have been observed in hairy cell leukaemia and chronic myeloid leukaemia. Seven other clones (producing IgG K anti-GAT antibodies) were derived from another fusion between NSI myeloma cells and spleen cells of (C57BL/6 X DBA/2)F1 hybrid mice hyperimmunized with GAT. Such a comparative approach is now further aided by the biokinetic modeling approach which can be used to predict the rates and routes of metal bioaccumulation and assist in the interpretation of accumulated body metal concentrations in aquatic animals.

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Sleep is a neuronal function, and it can no longer be postulated that one or more anatomical structures fully control sleep. Orthopaedic problems associated with survival in campomelic dysplasia.

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This paper discusses 10 of the most common burner and combustion system hazards that impact the safe operation of combustion equipment. Type of motion in inverted self-motion perception induced by a foreground stimulus. To compare individual exercise performance, published data tables obtained from field tests may be used.

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Consequently, gravid patients who have an AF-AFP incidental to chromosomal studies, and elect abortion because of a raised AF-AFP, will more frequently abort a normal fetus than the gravida who has previously had an infant with ASB. A standardized and common detection method is, therefore, essential for further routine SV40 analysis. Finally, potential use in the decontamination of wastewater or soils of the new adsorbent material has been compared with the most commonly used activated carbon and silica gel. Despite a significantly higher detection rate for hepatic metastases, CTAP has no added value in the therapeutic stratification in candidates for resection of hepatic metastases of colorectal cancer. Modified protein kinase activity and isozyme distribution in adenocarcinoma of the human colon.

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Finding JT in association with CREST syndrome suggests a common pathophysiologic process. Taken together, the available data suggests that lipoxins may have broad therapeutic potential in inflammatory disorders and could provide an alternative to corticosteroids in certain clinical settings. Overall, we present a fully degradable polymer system with nontoxic byproducts, which may find use in various biomedical applications including protein-based vaccines.

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Two dimensions of ethnic drinking culture-drinking prevalence and detrimental drinking pattern in the country of origin-were predictive of problematic heavy episodic drinking and drunkenness trajectories. Comparative analysis of essential genes and nonessential genes in Escherichia coli K12.

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Based on the capacity of crude extracts to phosphorylate exogenous histone, two of the mutants appeared to have altered cyclic AMP-dependent protein kinase (EC 2.7.1.37) and one of them had apparently normal amounts of kinase activity. Hypotonic fluids should not be used in volume-depleted children. Maternal antibodies in chicks one week of age were readily detected by the ELISA test, whereas low or insignificant titers were found by the VN test.

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Here we applied cortical pattern-matching algorithms to structural magnetic resonance images obtained from 21 children with confirmed 22q11.2 deletions (ages 8-17) and 13 demographically matched comparison subjects, in order to map cortical thickness across the medial hemispheric surfaces. Plastic surgeons are called upon to perform aesthetic surgery on patients of every gender, race, lifestyle, and religion. Further research into the connection of parasite burden with individual deaths and potential population declines is recommended for monitoring population health.