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Patients with both hard and soft drusen were studied using fluorescein angiography, swept-source optical coherence tomography (OCT), OCT-angiography, autofluorescence (both short-wavelength and near infra-red), scanning laser ophthalmoscopy in Multicolor mode. The purine 2-amino group as a critical recognition element for binding of small molecules to DNA.

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Theileria parva: early events in the development of bovine lymphoblastoid cell lines persistently infected with macroschizonts. Identification of the molecular mechanisms underlying dilated cardiomyopathy via bioinformatic analysis of gene expression profiles. Insufficient attention was paid to time and resources, dependency relationships, task specification, and communication and coordination. The characteristics of the rapidly adherent epidermal cells were determined.

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By analyzing a large series of patients with vulval and vaginal melanomas, this study sought to document the most common presenting features, identify clinical and pathologic predictors of outcome, and provide management guidelines. Our study suggested that NcGRA7 would be a new marker for the serodiagnosis of N. The purpose of this study is to determine the role of benign paroxysmal positional vertigo (BPPV) as a prognostic factor in patients with SSNHL. Studies on the structure of double-helix DNA in the last half century: Terminal structure of DNA An intraoral biopsy is necessary to confirm a definitive diagnosis in cases with similar clinical findings.

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Traumatic optic neuropathy: facial CT findings affecting visual acuity. Accurate levels of PaCO2 can probably only be obtained by frequent analyses of PaCO2, or monitoring of the end-tidal CO2 concentration. Here we address potential mechanism of ascorbate coupling with glutamate to generate oxidative stress, and the role which oxidized ascorbate (dehydroascorbate) transport plays in oxidative neuronal injury. Problems, diagnosis and differential diagnosis of primary pulmonary actinomycosis

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A 73-year-old woman visited our hospital 1 year 4 months ago because of multiple lung masses that were incidentally detected on CT. Before the signal denoising process, a key problem is how to choose a suitable wavelet base, decomposition level and denoising threshold, which have great influence on the quality of signal denoising. Pure annular dilation as a cause of mitral regurgitation: a clinically distinct entity of female heart disease.

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Seventeen components were preliminarily identified by HPLC-ESI-MS, including 9 hydrocinnamic acids, 4 anthocyanins, 3 flavonols, and 1 flavan-3-ol. As a result, the photocytotoxicity induced by folate-targeted liposomes was improved. This study suggests that persisters may be largely responsible for the multidrug tolerance of fungal biofilms. Two sequential reconstruction protocols were used to assess the contribution of the anteromedial and posterolateral bundles to restraining tibial translations and coupled axial rotation occurring with the manually performed clinical laxity tests.

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Selection of antisense oligodeoxynucleotides against glutathione S-transferase Mu. Nutrient profiling systems are confirmed to be powerful tools to translate nutritional information related to the whole diet into the level of individual foods.

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Cardiovascular magnetic resonance (CMR) is the gold-standard imaging modality for the assessment of myocardial structure and function. Structural insights into a yeast prion illuminate nucleation and strain diversity. In 67 controls (who were patients with nonmalignant gastrointestinal disorders, patients with gastrointestinal tumors other than colorectal adenocarcinoma, patients with other cancers, or healthy volunteers), negative reactions were obtained, with diverticular disease the only prominent exception. We hypothesized that patients showing good versus poor adjustment to cLBP mobilize cortical affective-cognitive functions differently in response to sensory stimulation and show increased reorganization of somatosensory cortex corresponding to the back. Advanced Glycation End Products (AGE)-Modified Proteins and Their Potential Relevance to Atherosclerosis.

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Preference weights (utilities) and prevalence-based quality-adjusted life-year (QALY) losses. Stabilization of fracture in one patient was made with metal plate and cables, stabilization with only cables was made to second patient. A new surgical technique for management of inner ear malformations with cerebrospinal fluid leakage

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The inhibition of platelet adenosine uptake may be related to some of the pharmacological properties of dipyridamole. To evaluate diagnostic value of Tei index in detection of chronic heart failure (CHF) in elderly outpatients. The transgene expression pattern in different tissues, which depends on vector serotype and route of administration, will need to be considered in planning therapeutic studies for specific disorders.

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We analyzed the contribution of pTP to pTP/pol origin binding using various DNA oligonucleotides. The distribution of cells active in the cell cycle within the normal and ototoxin-damaged vestibular epithelium suggests that supporting cells within the sensory epithelia are the cellular precursors to the regenerated hair cells. canimorsus, we identified a repA gene that allowed us to construct Escherichia coli-Capnocytophaga shuttle vectors. In the United States, the hereditary form disproportionately afflicts black Americans, who when compared with whites with wild-type transthyretin amyloidosis, a phenotypically similar condition, present with more advanced disease despite having a noninvasive method for early identification (genetic testing). Viable cells of each strain and their respective glycolipoproteins caused leukopenia, which occurs in the course of the lethal infection.

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Modification of levels of depression in mother-bereaved women by parental and marital relationships. Chlamydia trachomatis infection constitutes the most common sexual transmitted disease (STD) among young women.

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A 30-year-old male presented with spontaneous onset of painless progressive proptosis of the left eye, with diplopia. Despite the widespread use of up-down staircases in adaptive threshold estimation, their efficiency and usability in forced-choice experiments has been recently debated. Beginning at the heel, interrupted sutures are placed in such a way as to feed the redundancy of the donor artery wall towards the toe of the anastomosis. Spatial Metabolite Profiling by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging. Trigger points and acupuncture points for pain: correlations and implications.

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Retail sales of alcohol and the risk of being a victim of assault. Most of these were expressed at much lower levels than traditional reference genes, making them very suitable for normalization of gene expression over a wide range of transcript levels.

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A simple, inexpensive and sensitive method of detecting alpha-fetoprotein (AFP) by supplementation CIE assay is described. The late-phase of long-term potentiation (L-LTP), the cellular correlate of long-term memory, induced at some synapses facilitates L-LTP expression at other synapses receiving stimulation too weak to induce L-LTP by itself.

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Strains contained either macrolide-lincosamide-streptogramin B (MLSB) resistance genes encoded by erm(A) or erm(C) or a macrolide resistance efflux pump encoded by msr(A). The comparative proteomic expressive profiles of NB4-R1 cells treated with and without As(4)S(4) were obtained with the high-resolution two-dimensional electrophoresis system. Extended-spectrum beta-lactamase-producing Enterobacteriaceae in Bulgarian hospitals.

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Pheromone trails can be composed of two or more pheromones with different functions, and information may be embedded in the trail network geometry. The title compounds were 2-(1-butylthio)pyrimidine-4(3H)-one (5a), 2-(2-butylthio)pyrimidine-4(3H)-one (5b), 2-(cyclohexylmethylthio)pyrimidine-4(3H)-one (5c), 2-(benzylthio)pyrimidine-4(3H)-one (5d) and 2-(1-adamantylthio)pyrimidine-4(3H)-one (5e). In addition, vascular and myocardial CB1 receptors contribute to the modulation of blood pressure and heart rate. One of the proteins had an estimated molecular weight of 65,000-70,000, an isoelectric point of 4.6-4.8 and yielded a reaction of identity with bovine alpha 1-fetoprotein by immunodiffusion.

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Small doses of bosentan improve endothelial function without affecting hemodynamic parameters or endothelial activation-related processes, thus supporting a direct, reversible effect of endothelin in SSc-associated vascular injury. The former have been documented in the North Atlantic Ocean and Mediterranean Sea but not in the North Pacific Ocean, and the reasons for this are unknown. Possible pharmacokinetic and pharmacodynamic factors affecting parkinsonism inducement by cinnarizine and flunarizine. To determine the relevant sites for neurokinin-1 receptor activation in these midbrain regions, we examined the electron microscopic immunolabeling of neurokinin-1 receptors and the dopamine-synthesizing enzyme, tyrosine hydroxylase in normal rats.

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The confinement effect and the enhancement effect are attributed to the convergence of the power flow that passes through the annular aperture. Functional multiplicity of phosphoglucose isomerase from Lactobacillus casei. These feldspar-poor, quartzose sands contrast with highly feldspathic sands derived directly from a glacial source and probably transported through the Newfoundland abyssal gap onto the eastern and southern Sohm abyssal plain.

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albidus, and are indicative of the different degrees of stress resistance of these shrubs. Here the oral and esophageal mucosa, as well as tonsils, are demonstrated to be potential sites for viral infection upon nontraumatic oral exposure to SIV in macaques. The priming effect of glucose in soil sterilized by gamma-radiation and reinoculated with Cellulomonas sp. Inoculation of C57BL/6J mice with allogeneic P815 mastocytoma cells in the presence of simian virus 40 (SV40), a DNA tumor virus, led to an enhanced cytolytic T-cell response to P815 in vivo.

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These cells were transplanted into the cerebral cortex of adult rats with survival time of 5 days and studied by glial fibrillary acidic protein (GFAP) immunohistochemistry and electron microscopy. Calculating the Social Rhythm Metric (SRM) and Examining Its Use in Interpersonal Social Rhythm Therapy (IPSRT) in a Healthy Population Study. Lactate dehydrogenase (LDH) activity in serum increases as a marker of cellular necrosis. We confirmed that ATG16L1 and IL23R are susceptibility loci for CD in Hungarian CD patients. Among the noncommunicable diseases, is obesity, which has become a global epidemic associated with urbanization.

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The lack of widely accepted data, non consensus of scientists over nutrient removal mechanism and inability to apply performance standards observed in other countries directly might have hampered the acceptance of this technology in India. After the 1988 World Health Assembly resolution to eradicate polio, the number of countries where polio is endemic decreased from 125 in 1988 to six in 2003. Incidental, nonfunctional pancreatic endocrine tumors (PET) are observed with increasing frequency.

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Further degradation occurs after the removal of the free amino acids from the peptide mixture. Quest for diastolic prognostic indicators of clinical outcome after acute myocardial infarction.

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In the other 2 cases ultrasound did not specifically diagnose the lesions but did allow assessment of vascularity. However, a major limitation to the therapeutic value of CG antigen-directed vaccines is the limited and heterogeneous expression of CG antigens in tumors. Association of the protein C promoter CG haplotype and the factor II G20210A mutation is a risk factor for cerebral venous thrombosis. The ferrichrome receptor A as a new target for Pseudomonas aeruginosa virulence attenuation. Histochemical evaluation of delta 5,3 beta-OHSD activity in two types of porcine corpora lutea and granulosa cells in tissue culture.

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Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on In Silico Modeling of Published Data. These devices are in increasing use for diabetes therapy, although reliable data on subcutaneous insulin absorption is required to optimise their programming. This community-based health promotion initiative introduced traditional Indigenous games into schools and community groups in Cherbourg and Stradbroke Island (Queensland, Australia). A combination of 25-second delay CT and 75 mL of iodinated IV contrast can improve the diagnostic accuracy for lateral lymph node metastasis from papillary thyroid carcinoma compared with a combination of a 35- or 70-second delay with 100-mL of iodinated IV contrast. Other indicators may be important for DNA photonic detection, and besides being more expensive, they behave similarly to EthBr.

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The rat model of hyperlipidaemia was established by feeding high lipid diet with cholesterol for 6 weeks. The results showed that, 1) genuine age-related decline was found in speech perception performance in HINT (NF), 2) hearing threshold was a major determinant differentiating speech perception performance for HINT (Q) and HINT (NL) conditions, and 3) speech perception performance for HINT (NR) was determined by both age and hearing threshold. Bowel obstruction following appendectomy: what is the true incidence? Curve fitting in the Fourier domain offers an attractive alternative for parameter estimation. monocytogenes-immune peritoneal exudate T-enriched cells (PETLEs) together with 5 X 10(4) living L.

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Interaction of RNA polymerase of Escherichia coli with substrate by affinity labeling and NMR with nuclear 31P Evidence suggests that improved health care technologies generally increase rather than reduce health care expenditures. Inhibition of cyclooxygenase-2 in experimental severe acute pancreatitis. In one nucleus studied on ultrathin sections the perinucleolar chromatin was found to be more sensitive to EDTA than the chromatin of other parts of the nucleus. aureus suppressed the antigen-induced proliferation of peripheral blood mononuclear cells.

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The use of HInCl2 generated slowly in situ is extremely effective for the radical cyclization. The gene for LAg42 is conserved among pathogenic leptospires but not among non-pathogenic leptospires, which suggests its involvement in virulence. To investigate the underlying metabolomic profifiling of coronary heart disease (CHD) with blood stasis syndrome (BSS). There is a difference in the control of secretion of these proteins dependent on the gestation, suggesting that there is a tight regulation in the function of first-trimester trophoblasts depending on the gestational age.

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Industry recruitment was done after a careful assessment of capability and willingness. These findings suggest a potential therapeutic approach to prevent age-related retinal dysfunction. Possible precipitating factors for NCSE include benzodiazepine withdrawal, excessive use of psychotropic drugs, and electrolyte imbalances. Two-photon entanglement generation: different Bell states within the linewidth of phase-matching. Correlation of radiographic measurements of structures of the equine foot with lesions detected on magnetic resonance imaging.

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This analysis is verified experimentally with data from acriflavin stained Sephadex beads. A role for the C2 domain of factor VIII in binding to von Willebrand factor.

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Adatom surface diffusion of catalytic metals on the anatase TiO2(101) surface. C5-C10 directly bonded tetrodotoxin analogues: possible biosynthetic precursors of tetrodotoxin from newts. Here, we analyse the expression of the neurogenic gene Ol-DeltaA in the brain of medaka (Oryzias latipes) embryos and adults. Some of the excreted proteins are interesting targets for further genetic and physiological studies. In particular, it is known that GSLs have numerous physiological functions due to variations in the sugar chain, in spite of the very small quantity of constituents.