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Involvement of histamine in growth of mouse and rat tumors: antitumoral properties of monofluoromethylhistidine, an enzyme-activated irreversible inhibitor of histidine decarboxylase. The Satter Eating Competence Inventory for Low-income persons is a valid measure of eating competence for persons of higher socioeconomic position. Superoxide dismutase (EC 1.15.1.1) activity was investigated in several types of neural cells cultivated in the presence of 100 mM ethanol. Isolation and characterization of the Aspergillus nidulans eglC gene encoding a putative beta-1,3-endoglucanase.

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It has been proposed that amplification and homogenization of satellite DNA could be facilitated by extrachromosomal circular DNA (eccDNA) molecules originated by recombination-based excision from satellite repeat arrays. In addition to its antimicrobial action, other activities have been described in eukaryotic cells that may contribute to the healing response. Imaging-based analysis demonstrated ASC localization in the top layer of skin and a higher density of regenerating blood vessels in the treated groups. Eighteen patients who had not had previous otological surgery, and twelve patients whose tympanic membrane perforations have persisted despite myringoplasty with temporalis fascia were included in this prospective clinical trial. Emotional and behavioral disturbances in school going HIV positive children attending HIV clinic.

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UV resonance raman investigation of electronic transitions in alpha-helical and polyproline II-like conformations. Demographical data of the physicians was collected prospectively. Identification of bacterial carotenoid cleavage dioxygenase homologues that cleave the interphenyl alpha,beta double bond of stilbene derivatives via a monooxygenase reaction. A docking site for phosphoprotein phosphatase-2A in the DEP domain of Dishevelled-2 was identified. The drugs were equal in terms of analgesic efficacy, duration of analgesia and onset of action.

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Probes (antibodies, PCR) were tested for specificity, but might have non-specific reactions. Moreover, since the effective titres of delivered Ad5 are reduced with this neuron specific promoter/WPRE expression cassette, the viral immune challenge should be attenuated when used in vivo. The spatial organization of nucleolar DNA in phytohemagglutinin-stimulated lymphocytes of the guinea pig. Also the type of the used stationary phase has found to play an important role in retention behaviour of beta-blockers.

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Frequency affected the SHAT response parameters, with significant phase differences between the frequencies 0.01, 0.02, 0.05, 0.1, and 0.2 Hz, while velocity, if kept below 150 degrees/s, had no influence on the results. Tracking of non-adherent patients by health workers could further improve outcomes.

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The eventual place of thermotherapy in the treatment of malignant tumours in man is as yet unclear and must be rigourously and thoroughly assessed in well-designed, prospective, randomized patient trials. Single-centre trial, study period from October 2013 to January 2014. Mathematical modeling of thymopoiesis in HIV infection: real data, virtual data, and data interpretation.

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This response occurring in the absence of estrogen receptors suggests that the action of estrogen on nasopharyngeal angiofibromas is indirect. However, rhIFN-beta retained its sleep-promoting action after heat treatment, suggesting that microbial contaminants were responsible for its somnogenic and pyrogenic activities. The titanium prosthesis analysed in this study demonstrated optimum acoustic-mechanical behaviour. Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear export.

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Twenty Years of Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy. Four weeks of atorvastatin therapy significantly increased HDL-C, PON1 activity and reduced LDL-C, TBARS and lipid peroxide concentrations.

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Different PEEP levels were applied (14 to 0 cm H2O, in steps of 2 cm H2O) and blood gases, Vcap and EIT were measured. The CHiPS Domain--ancient traces for the Hermansky-Pudlak syndrome.

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Fourteen patients were included in the induction of tolerance protocol. Additional trials are needed to better define the benefits and risks of oral antidiabetic agents in pregnancy. Computed tomography and angiography of hepatocellular carcinoma. The predictive roles of symptom combination traditionally evaluated in traditional Chinese medicine (TCM) in the treatment of rheumatoid arthritis (RA) were explored. In this article we review the literature on the use of ARB drugs in general before focusing on candesartan.

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Angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade have provided equivalent renal benefits, and their dual action seems to confer greater renoprotection. The generation of superoxide has been implicated as a cause of cochlear damage from excessive noise. Implications of the results and the use of EMG measurement to help identify patient candidates for splinting are discussed. Two diphenylpropan-1,2-diol syringates from the roots of Erythrina variegata. Proceedings of the XIIth Congress of Public Health Research, March 2007, Mexico

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The basic concepts of eCAP recordings are deduced from the acoustical equivalent of the electrocochleogram. Self-compatibility of two apricot selections is associated with two pollen-part mutations of different nature. Theoretical advantages are described, current knowledge reviewed, and an outline of a prospective study presently underway is given. During January 24-May 9, 2003, smallpox vaccine was administered to 36,217 civilian health-care and public health workers in 55 jurisdictions to prepare the United States for a possible terrorist attack using smallpox virus. Tissue samples were obtained before and after radiosurgery in a patient with a malignant (Grade III) cerebellar astrocytoma.

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The volume of crevicular fluid around full crown restorations was measured with a Periotron instrument to compare the gingival inflammation between restored and nonrestored teeth in the same patient. In order to explore the involvement of the cyclin-dependent kinase inhibitor p16(INK-4a) in UVB-induced premature senescence, we developed an original model of repeated sublethal exposures of human keratinocytes deficient in p16(INK-4a). We reported a 69-year-old woman who had NCSE of frontal origin manifesting prolonged somatic hallucinations mimicking a psychiatric disorder and initially treated as such.

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In other tissues the levels of the drug were relatively lower (8.1-42.8 microg/g of wet tissue). Assessment of in situ host immunity to syngeneic tumors utilizing the multicellular spheroid model.

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This study was retrospective and involved a mail-out survey to 2610 users of the Silver Chain Care Link Personal Alarm Service. To include the vast array of interrelated derangements, and to stress the bi-directional nature of the heart-kidney interactions, the classification of the cardiorenal syndrome includes today five sub-types whose etymology reflects the primary and secondary pathology, the time-frame and simultaneous cardiac and renal co-dysfunction secondary to systemic disease.

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aeruginosa has a cyclic nucleotide-dependent natriuretic peptide sensor system that may affect virulence by activating the expression of Vfr and LPS biosynthesis. Measurement of the spatial redistribution of water in rabbit Achilles tendon in response to static tensile loading.

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The recognition of this milk-like fluid as chyle is urgent for the implementation of the correct treatment. Here, we present the expanded trans/supraorbital approach to overcome these limitations. Two new methoxy lactone chlorins ficusmicrochlorin A (1) and ficusmicrochlorin B (2), and one new anhydride chlorin ficusmicrochlorin C (3), along with eight known pheophytins were isolated from the leaves of Ficus microcarpa. A high dose of gefitinib (200 mg/kg/day) administered during the late phase significantly reduced fibrosis scores and collagen levels.

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Use of space-time models to investigate the stability of patterns of disease. Artemether-lumefantrine (AL), presently the most favoured combination therapy against uncomplicated Plasmodium falciparum malaria in Africa, has recently shown to select for the pfmdr1 86N allele. Although medulloblastoma is said to be capable of astrocytic differentiation, the development of an astrocytic neoplasm in association with a medulloblastoma is extremely rare. This review describes some of the characteristic morphological features which can be demonstrated in neoplastic cells by electron microscopy and briefly considers several areas where the technique is of special value.

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HCMV infection of human vascular smooth muscle cells leads to enhanced expression of functionally intact PDGF beta-receptor. DNA damage (single or double-strand breaks) triggers adapted cellular responses. With a tissue optics plug-in for the GEANT4/GAMOS system and published ex vivo tissue optical properties we were able to predict the behavior of different device configurations when used with varying thicknesses of fat, melanin concentrations or hydration levels. We demonstrate that the feedback mechanism proposed in this article synergizes with such enzyme depletion effects to bring about a much larger bistable range than either mechanism alone.

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The author describes the context in which this transformation has occurred and the factors that caused the USC medical school to move from a position of relative insularity from the other colleges within the university--conducting little extramural research, and regarding its relationship with its teaching hospitals as distal, associated institutions--to a position of full integration into the Division of Health Sciences with very significant growth in externally funded research and closer-than-ever-before working relationships with its two teaching hospitals. The DNA binding protein nuclear factor-kappaB (NF-kappaB) is a transcription factor translocated from the cytosol to the nucleus in response to stressors. An optimally tapered matching solves two problems simultaneously: it optimally divides the single comparison population into nonoverlapping comparison groups and optimally pairs members of the focal group with members of each comparison group.

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The method will be useful in the synthesis of natural products and will facilitate the synthesis of previously inaccessible contra-thermodynamic acetals. Studies on the variations of eosinophilia in the diagnosis of human echinococcosis These cells constantly scan the brain and react promptly to any abnormality, removing detrimental factors and safeguarding the central nervous system against further damage. The phylogeny of endolithic microbes associated with marine basalts. To characterise the prognosis and identify factors contributing to mortality in patients with tuberculous destroyed lung (TDL).

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The presence of a founder mutation from Newfoundland is strongly supported. Specific ligands targeting TSPO increase neurosteroid production and for this reason they have been suggested to play an important role in anxiety modulation.

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We find that the induction of inducible NO synthase (iNOS) and cytokines is suppressed in mice with DIO and in bone marrow macrophages (BMMPhi) from mice with DIO exposed to an oral pathogen, Porphyromonas gingivalis. Despite the partial defect in both GEF and GAP regulation, KRAS K104Q did not alter steady-state GTP-bound levels or the ability of the oncogenic KRAS G12V mutant to cause morphologic transformation of NIH 3T3 mouse fibroblasts and of WT KRAS to rescue the growth defect of mouse embryonic fibroblasts deficient in all Ras genes.

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The Israeli case provides an interesting example of nation-wide, long-term implementation of the pay-for-performance program. Plant microRNAs (miRNAs), a class of small non-coding regulatory RNAs, are canonically 20-24 nucleotides in length and bind to complementary target RNA sequences, guiding target attenuation via mRNA degradation or translation inhibition. Subjects with PACG, PACS, or PAC were pooled into a group considered to have angle closure. Cyclooxygenase-2 (COX-2) and interferon gamma (IFNgamma) are overexpressed in vascular inflammatory and atherosclerotic lesions.

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Combination therapy with pentostatin seems to provide response frequencies comparable to fludarabine based combinations but with less toxicity and with greater ease of administration. The functional evaluation of the recombinant hTPOs showed decreased activity in the three mutants with respect to WT. Our findings have important implications for inferences about the mechanisms underlying the exceptional clinging capabilities of geckos, including whether performance of free-ranging animals is based solely on a dry adhesive model. I-PREDICT study identified factors that can be targeted for improving BP control.

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In the context of this study, we define an effective pattern as that in which muscles whose mechanical contribution to the task is greatest, are mostly active, while the antagonist muscles are mostly silent. standard non-rebreather oxygen face mask in post-extubation intensive care unit patients. This study was performed to assess the extent of agreement among radiologists and nonradiologists in perception of diagnostic certainty conveyed by words and phrases commonly used in radiology reports.

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To examine the clinical effects of electroconvulsive therapy (ECT) on depressed patients with medication treatment failures, we investigated the alterations in hypothalamic-pituitary-adrenocortical (HPA) function and regional cerebral metabolism rate of glucose (rCMRGlu) after ECT in these patients. The antibacterial activities of erythromycin, azithromycin, and clarithromycin antibiotics against the recovered isolates of 779 nasopharyngeal swabs were examined using MIC (Minimum Inhibitory Concentration) method. This study was designed to investigate the vascular endothelial growth factor (VEGF) and the microvessel density(MVD) in node-negative breast carcinoma, and to discuss the relationship of MVD and VEGF to the tumor size, histologic grade, and relapse and metastasis. HIV drug prices used in national programmes (2010-2014) were extracted from the WHO Global Price Reporting Mechanism database for all reporting middle-income countries as classified by the World Bank.

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These results identify one of the mechanisms schistosomes use to escape immune attack. Several such Gcd(-) mutations alter the A928:U1389 base pair in helix 28 (h28) and allow PICs to scan through the start codons of upstream ORFs that normally repress GCN4 translation. Thrombolytic activity of BB-10153, a thrombin-activatable plasminogen.

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Isolation of ascorbate free radical reductase from rabbit lens soluble fraction. Cutaneous vasculitis and reactive arthritis following respiratory infection due to Chlamydia pneumoniae: report of a case. The antibody-drug conjugate (ADC) cAC10-vcMMAE consists of the tubulin inhibitor monomethyl auristatin E (MMAE) conjugated to the chimeric anti-CD30 monoclonal antibody cAC10.

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After 10 weeks, bladders were removed, sectioned, and stained with haematoxylin and eosin. Motor Training Promotes Both Synaptic and Intrinsic Plasticity of Layer II/III Pyramidal Neurons in the Primary Motor Cortex. Each sequence is assumed to be composed of blocks of equal length and its fitness is given by a linear combination of four independent block fitnesses. Chemotherapy and high dose radiotherapy followed by resection for locally advanced nonsmall cell lung cancers.

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We found that LCACEs inhibited phosphorylation of AMPK by the recombinant AMPK kinase (AMPKK) LKB1/STRAD/MO25 in a concentration-dependent manner. The role of the CIDI as the reference standard should be reexamined, as older alcohol-dependent patients with severe comorbidities seemed to be missed in this assessment.

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Microscopic visualization of the retina by angiography with high-molecular-weight fluorescein-labeled dextrans in the mouse. Periradicular cemental dysplasia is indeed a new NF1 related bone lesion type. However, formulations also enriched with n-3-fatty acids and ribonucleic acids lower the risk of several wound complications, thus being more effective than isolated arginine.

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Patients with primary mRCC treated with first-line sunitinib were selected from a Dutch population-based registry. Fast high-precision on-line determination of hydrogen isotope ratios of water or ice by continuous-flow isotope ratio mass spectrometry. Serial renal histology demonstrated progressive mesangial proliferative glomerulonephritis.