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Gabtin (Gabapentin)

Gabtin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabtin has some stark advantages as compared with other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and lack of appreciable metabolism making it unlikely to participate in pharmacokinetic drug interactions. It is structurally and functionally related to another GABA derivative, pregabalin.

Other names for this medication:
Gabapentin, Neurontin, Algia, Alpentin, Bapex, Blugat, Dineurin, Edion, Epleptin, Gabagamma, Gabalept, Gabanet, Gabaneural, Gabantin, Gabapen, Gabapentina, Gabapentine, Gabapin, Gabaran, Gabatal, Gabateva, Gabatin, Gabatine, Gabator, Gabax, Gabex, Gabexal, Gabictal, Gabiton, Gaboton, Gabrion, Gabtin, Galepsi, Ganin, Gantin, Gapridol, Gatilox, Gordius, Kaptin, Neurexal, Neuril, Neuropen, Neuros, Neurotin, Nupentin, Pendine, Progresse, Ritmenal, Tebantin,

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Lanzopral, Vagimid, Dofil, Nortylin, Naxy, Levozine, Promox, Oroken, Uromax, Fexodine, Amoxiplus, Levofloxacin, Sporanox, Primadex, Panzo, Metryl, Nupentin, Zitrocin, Gastrium, Bazetham, Zoldicam, Incivek, Bacticel, Ulcesep, Depolan, Clindagel, Pantelmin, Pantul, Cefakind, Ansial,

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At moderately strong fields this state is stable for quite long times. Ten patients diagnosed as inoperable Stage IIIB NSCLC with comorbid disease were assessed retrospectively in Bezmialem Vakif University, Faculty of Medicine, Department of Radiation Oncology, between 2011 to 2013.

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In 1989, researchers discovered that amphibians, particularly frogs and toads from many parts of the world, appeared to be declining. In agreement with these results, gamma-irradiation-induced apoptosis in BMMC was shown to be dependent on p53 whereas apoptosis induced by deprivation is partly dependent on p53, implying that there are other mechanisms mediating apoptosis in KL-deprived BMMC. Recently, it was demonstrated that certain chemokines require interactions with GAGs for their in vivo function.

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Furthermore, pretest coadministration with lithium of a dose of L-arginine (0.0001 microg/mouse, i.c.v.) or L-NAME (0.0001 microg/mouse, i.c.v.) that had no effects when administered alone, increased the effect of lithium on retrieval of inhibitory avoidance memory. A dynamical programming approach is used to deal with the problem of controlling the directed abelian Dhar-Ramaswamy model on two-dimensional square lattice. Parathyroid surgery is often challenging due to considerable variability in anatomy. Fabricating TMA mold using silicone in the department is inexpensive and yet efficient. The old injury site presented the same sequelae of changes as seen in other lesioned animals.

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Further discussion and research are mandatory to decide on optimal management of these patients, with regard to monitoring, fluid management, and the precise timing and mode of delivery in order to prevent fatal morbidity and mortality to both mother and fetus. Cross-sectional areas (CSAs) of the ulnar nerve were measured 4 cm proximal to the medial epicondyle (CSA-prox), 4 cm distal to the epicondyle (CSA-dist) and at the maximum CSA (CSA-max) of the ulnar nerve found between these points. The listeners were groups of younger and older persons with or without hearing loss.

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We conclude that ITP and IEF separate IgG into corresponding patterns. In addition, mitochondria subsequently exhibited increased reactive oxygen species production and membrane potential. In this study, we investigated the mechanism(s) by which Tau-Cl inhibits LPS-induced NO production in macrophages. Our results have shown that normal human keratinocytes and fibroblasts in culture express the LAD target antigens.

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Computer-assisted surgery will contribute to reproducible and accurate placement of implants. Strong proliferative responses (MLR) were detected only in the secondary cultures, for which H-2 homology was also required between TNP-modified primary and secondary immunogens.

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It is suggested that caution is exercised during gynecologic procedures to avoid transplantation of endometrium to the anterior abdominal wall. Comparing hemodynamic responses to 0.5 microgram/kg of PGI2 of the conscious and anesthetized states, decrease in PSA was smaller and increases in CO and HR were greater in the former. Multiple logistic regression models were fitted to estimate risk factors of previous and present occupational injuries. oryzae NRRL 395 resulted in reductive LDH activity between 1.0 and 1.8 U/mg total protein. Based on random-effects Probit estimates, these two questions can be answered as follows.

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Surface stress: a factor influencing ultra high molecular weight polyethylene durability in mobile-bearing knee design. Apoptosis as well as necrosis may play an important role in hepatic ischemia/reperfusion (I/R) injury. Smoking did not seem to influence the relationship between asthma and body mass index. Usually LDF time series are analyzed by conventional linear methods, mainly Fourier analysis.

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Thermodynamic approach to optimize immobilized metal affinity chromatography purification of protein C. Adenocorticotropic hormone (ACTH), cortisol, growth hormone (GH), and urinary 17-hydroxysteroids were also normal.

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The Wnt5a effect on axon differentiation was attenuated by downregulating Dvl or inhibiting aPKC. Several previous studies have predicted that carboxypeptidase-E (CPE), prohormone convertase 1 (PC1) and prohormone convertase 2 (PC2) may function as sorting elements for somatostatin (SST) for its maturation and processing to appropriate targets.

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The ventilatory response to hypercapnia was found to be significantly decreased in the elderly subjects. However, the mobilization, recruitment, and functional capacity of endothelial progenitor cells are significantly impaired in diabetes. Biopsy can acquire the qualitative diagnosis on atlanto-axial tuberculosis. Improved survival for these patients will likely require combined therapy that includes novel treatment. The free radical initiator Vazo 68 is coupled to a peptide and electrosprayed into an ion trap mass spectrometer.

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These results suggest that overcoming a phosphatase may be sufficient to induce secretion in RBL-2H3 cells, and that this secretion may be regulated by F-actin and myosin rearrangements. TNF-alpha induces insulin resistance on glucose uptake in human visceral but not sc adipocytes, suggesting depot-specific effects of TNF-alpha on glucose uptake.

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The effects of AM 404 (0.015-2 mg kg(-1)) and THC (0.05-2 mg kg(-1)), given 5 min after ischaemia, were measured from 1 h to 7 days in terms of electroencephalographic (EEG) total spectral power, spontaneous motor activity, memory function, rectal temperature and hippocampal CA1 neuronal count. This may contribute to the initial burst of virus replication that is observed in these cells.

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This paper reviews the literature pertaining to both treatment modalities and identifies key issues that need careful consideration in planning the most appropriate course of care in a given clinical situation. Fetal interventions have the potential to alter the natural history of abnormal cardiac development. To test whether drinking onset moderates genetic and environmental contributions to individual differences in the etiology of alcohol expectancies across adolescence. platelet-derived growth factor, transforming growth factor beta), but also by those generated at sites of vascular injury from inactive precursors circulating in the blood (e.g.

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The increase of the viscosity and decrease of the density impair the results of the examination. Studies in the experimental mouse pituitary tumor cell line AtT-20/D-16-v have recently shown that ACTH, the lipotropins (beta- and gamma-LPH), beta-endorphin (beta-End) and the 16-K fragment are synthesized through a common precursor molecule which is a 31,000 glycopeptide (pro-ACTH/endorphin). A structured interview was conducted to identify normal patterns of oral care and dental attendance and to elicit if since suffering a stroke any changes had occurred or were likely to occur. Hg and above were found to be indicative of bladder outlet obstruction. Neutralizing human anti-B-cell-activating factor of the TNF family (BAFF) scFv selected from phage antibody library.

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Re: Radiation Exposure from Diagnostic Imaging in Young Patients with Testicular Cancer. This is a case report of an environmental accident due to lightning where one school boy sustained current, blast, and flame effects of it. We examined the mRNA and protein expression of KCa channel genes (KCNMA1, KCNN1, KCNN2, KCNN3, and KCNN4) in both cell types.

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It is not clearly shown whether the prognostic factors are identical in relation to the type of diabetes. Effect of fiber treatments on tensile and thermal properties of starch/ethylene vinyl alcohol copolymers/coir biocomposites.

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Prolonging survival in prostate cancer: chemotherapy will have an important role. Protein structure was determined by infrared spectroscopy and intrinsic fluorescence.

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From the data presented, it is postulated that early complications provide no decisive reason for treating femoral neck fracture as an emergency. The accuracy of saccadic eye movements made by trained Cebus monkeys was studied during reversible lesions produced by cooling through probes implanted between the interpositus and fastigial nuclei (medial probe) or lateral to the dentate nucleus (lateral probe). Meta-analysis is the systematic and quantitative synthesis of effect sizes and the exploration of their diversity across different studies. The paper presents a Fourier transform-based signal processing procedure for quantifying the reflection and transmission coefficients and mode conversion of guided waves diffracted by defects in plates made of viscoelastic materials.

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Only CaTrk1 was properly recognized and secreted to the plasma membrane. A strategy of empyema tube drainage with staged removal is an option in appropriately selected patients with chronic empyema, unexpandable lung, and poor surgical candidacy. Here, we describe the use of bacterial artificial chromosome (BAC) transgenesis to target Cre expression to tissues that express steroidogenic factor 1 (SF-1, officially designated Nr5a1). There was not enough evidence to assess the effects of adrenergic agonists when compared to or combined with other treatments. Many studies have underlined the reasons for medical care failure caused by an inability to sustain a resistant behavior towards palatable food (high sugar and fat content).

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In patients with moderate or no hepatic failure, the commonest actively bleeding sources were oesophagogastric varices and acute mucosal ulcers associated with the ingestion of anti-inflammatory drugs. Agreements between the prothrombin times of blood treated In Vitro with heparinase during cardiopulmonary bypass (CPB) and blood sampled after CPB and systemic protamine. LMP, HMP, and aSBM decreased the relative abundance of the genus Lactobacillus and increased that of Prevotella in the colon. The mitotic exit network Mob1p-Dbf2p kinase complex localizes to the nucleus and regulates passenger protein localization. We incorporated these findings into a new model of the masticatory central pattern generator.

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Heat shock reduces developmental competence and alters spindle configuration of bovine oocytes. The overall prevalence of advanced colorectal neoplasm in asymptomatic Asians is comparable with the West. Domoic acid (DOM) is known to cause hippocampal neuronal damage and produces amnesic effects. The resultant FITC Thy-1 antibodies suffer little loss in cytotoxic properties, react with the correct specificity and can be used to label Thy-1 positive cells. After peripheral axotomy, mammalian spinal motoneuron dendrites have been shown to cyclically degenerate and regenerate and after spinal dorsal horn mince to initially increase in length and then atrophy with time.

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Bilateral parallel-opposed fields are matched to anterior lower neck field. The purpose of this economic analysis was to estimate the potential economic benefits of the differences in direct health care costs attributable to the prevention of first and recurrent strokes in the HOPE Study patient population through the use of ramipril. The effect of timing of skin grafts on subsequent survival in ALS-treated, marrow-infused mice.

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Effect of fenofibrate in combination with urate lowering agents in patients with gout. The discrepancy between the estimated model parameters is small, and essentially the same descriptive process model is obtained.

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RNA and proteins were extracted and processed for reverse transcription (RT) coupled to polymerase chain reaction (PCR) and Western blot, respectively. Further research is necessary to substantiate the findings of the study.

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The efflux transporter P-glycoprotein has recently emerged as a major determinant of drug disposition in humans. Global cerebral ischemia: effects of pentastarch after reperfusion.

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This model suggests future applicability in reperfusing segments of retinal arterioles or venules that have been obstructed by naturally occurring pathologic processes. They developed clinical and radiological changes of diffuse interstitial pneumonia, characterised by an inflammatory syndrome, restrictive changes on spirometry, reduced CO transfer and abnormal blood gases. After 31 patients underwent endoscopic full-thickness resection, the data were analyzed retrospectively.

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Fine mapping of a continuous epitope on VP7 of bluetongue virus using overlapping synthetic peptides and a random epitope library. brucei and validate the corresponding peroxidases as targets for drug design. This analysis was less successful than denaturing gradient gel electrophoresis in detecting the eight unique mutations. The BMD may prove to be a suitable diagnostic tool for clinicians. Betrayal trauma: relationship to physical health, psychological distress, and a written disclosure intervention.

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Serum bone alkaline phosphatase, a marker of bone formation, was increased at week 2 compared with the basal level. We identify a striking elevation in expression of the proximal tyrosine kinase Zap70 in resting Ag-specific and polyclonal mouse memory vs naive CD4 T cells that is stably maintained independent of protein synthesis. Endostatin is a naturally occurring proteolytic fragment of the C-terminal domain of collagen XVIII.

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In women with the latter condition the plasma concentration of vasopressin is several-fold higher than that in healthy control persons. Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. Possibilities for the dissemination of microorganisms in a hospital environment This confirms the importance of the theoretically predicted stripes of compressible and incompressible electronic states close to the boundary of the QHE devices.

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The aim of study was to estimate the safety and efficacy of using laser wavelength of 1560 nm with the foam sclerotherapy (FS) of varicose veins (VVs) for the treatment of severe primary chronic venous insufficiency (CVI, C4-C6) in patients with different diameters of the proximal segment (DPS) of the great saphenous vein (GSV). Both purified proteins showed a major protein band with a molecular weight of 33,000 and a few faint bands in sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis under reducing conditions. More than half of the commensal serotypes obtained in the study as well as majority of the systemic serotypes were observed in ophthalmic infections.

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To review the use of selective serotonin-reuptake inhibitors (SSRIs) in the treatment of premature ejaculation. The gut is comprised of an eversible pharynx, esophagus, intestine and rectum. Totally, 292 ANA-positive and 292 matching ANA-negative patients were included in the study. A systematic review of the nonsurgical treatment of patients with appendiceal abscess or phlegmon, with emphasis on the success rate, need for drainage of abscesses, risk of undetected serious disease, and need for interval appendectomy to prevent recurrence. There was no leakage of radioactivity from the bandage when tested in saline.

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HAC-Cytoxan (cyclophosphamide) chemotherapy for ovarian carcinoma. Cytomegalovirus retinitis after treatment with lenalidomide for multiple myeloma. This review summarizes our current understanding of the epidemiology and molecular-genetic bases of these malformations, as well as recent neuroradiological and clinical studies, which have revealed that the manifestations of holoprosencephaly are far more variable than previously appreciated. After the system was flushed, IBP was measured with 25 ml increments up to 300 ml.

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There was no significant difference in lung volumes in patients or control subjects over the 3 days. The mixture of neurotrophic factors and ductus was implanted to the neural tube wall which could be degraded then releasing factors slowly. Shoulder-Muscle Activation in Individuals With Previous Shoulder Injuries. Poor psychological functioning (i.e., depressive and anxiety symptomatology), rather than poor physical health, may have the strongest implications for long-term cognitive functioning in older men and women. In contrast, no DSBs were observed after exposure of Chinese hamster cells to cisplatin, another crosslinking agent widely used for the therapy of various cancers, challenging a common role for DSBs in the processing of DNA interstrand crosslinks.

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Increased understanding of the angiogenic process, the diversity of its inducers and mediators, appropriate drug schedules and the use of these agents with other modalities may lead to radically new treatment regimens for many of these conditions. To further unravel intra- and interspecies PTLV-1 evolution in Asia and Africa, we phylogenetically analysed 15 new STLV-1 LTR and env sequences discovered in eight different Asian and African non-human primate species.

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We used data from the Stockholm Heart Epidemiology Program, a population-based case-control study conducted during 1992-1994, to study the association between myocardial infarction and the daily intake of drinking water magnesium and calcium. Suppression subtractive hybridization (SSH) was used to isolate genes differentially expressed following exposure to copper (Cu) in a naturally selected Cu-tolerant birch (Betula pendula Roth.) clone originating from a disused lead/zinc smelter.

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The poor response to angiotensin infusion may have been caused by inhibition of ACTH release, a phenomenon shown to occur in king pandon review normal human subjects. Cardiac protection induced by intermittent hypoxia is critically dependent on Hif1a gene dosage. Thus to withstand strong forces from chromosome dynamics an anchoring tether is likely to be much more complex than a single protein-protein or protein-DNA interaction. Then, other clinicopathologic variables for prognosis were evaluated using univariate and multivariate analyses.

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Whether leanness is related to an increased risk of lung cancer is controversial. Immunohistochemistry metronidazole topical cream 0.75 interactions showed that administration of capsaicin to newborn rats depleted irreversibly the neuropeptide, substance P. We analyzed the expression of ten reference genes in male and female samples over three stages of brain development, using popular algorithms NormFinder, GeNorm and Bestkeeper. Because high intake of saturated fat is a major risk factor for ischemic heart disease, we tested the hypothesis that chronic (18 weeks) consumption of a high saturated fat diet increases susceptibility to IRI, an effect more marked in the HGI rats than in the H rats. These results demonstrate that different experimental manipulations and factors which do not strictly depend on genetic diversity between donor and recipient profoundly affect allogeneic BMT.

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Our series included 16 patients with traumatic unique injury to the long thoracic nerve. The modern methods of imaging, especially the digital photography, offer a wide spectrum of use in forensic medicine--the digital documentation and archivation of lisovyr acyclovir medication autopsy findings, the possibility of immediate consultation of findings with another experts via Internet, and many others. Unlike mammals, teleost fish are able to mount an efficient and robust regenerative response following optic nerve injury. Psychological experience of gambling and subtypes of pathological gamblers.

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Guillain-Barre syndrome (GBS) is an omeprazole dose for hydrocephalus in infants acute demyelinating polyneuropathy characterised by progressive muscular weakness and areflexia. These data show that Egr-1 contributes to increased LPS-mediated TNF-alpha expression after chronic ethanol and that the absence of Egr-1 prevents chronic ethanol-induced fatty liver, as well as increased sensitivity to LPS.

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There was no difference in body tetracycline hydrochloride mwafcu growth and mortality between the experimental and control groups. Molecular breast imaging was implemented in routine clinical practice at a large community-based breast imaging center.

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As expected after administration of allergodil nasal spray 10 ml to tsp DSS, mice manifest loss of body weight, shortening of colon length and bloody feces. Management of Common-law Marriage in Hospitalization for Medical Care and Protection Procedure after Abolishment of Guardianship System While we found that rapamycin binds the FRB domain and inhibits the kinase activity of mTOR even in the absence of FKBP12 (in the low micromolar range), our most potent ligands bind to FRB with similar binding affinity but inhibit the kinase activity of mTOR at much higher concentrations. Near-infrared luminescence of nine-coordinate neodymium complexes with benzimidazole-substituted 8-hydroxyquinolines. From neurodegeneration to neurohomeostasis: the role of ubiquitin.

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Technically, single fluoroscope is considered sufficient for effectively monitoring PV. In this article, we review two major obstacles facing alfalfa utilization, namely poor protein utilization and relatively high lignin content, and highlight genetic studies that were performed to overcome these drawbacks, sustained release gabapentin dosage as well as to introduce other improvements to alfalfa quality.

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T cell-specific human alloantisera-detecting antigens segregating outside the major histocompatibility complex. We suggest that the mitochondrial import machinery is capable of discriminating against the mutant RNA in favor of the normal tRNA for import. diabetic cataract, right eyes compared to left eyes, and presence/absence of uveitis. Combined silver staining of the nucleolus collins alboz pharmaceuticals organizing regions and Giemsa banding in human chromosomes.

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It is proposed that holocarboxylase synthetase and intestinal biotin absorption are defective in the early and late forms respectively. An improved method for extracting bacteria from soil for high molecular weight DNA recovery and BAC library construction. Across all groups, higher modularity and small-worldness strongly correlated with reduced distractibility on bupropion pregnancy risks an implicit priming task.

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The numerical model was then used to test the suitability of a range of different designs of permanent magnet assemblies for MDT. Exhaled nitric oxide levels in school children in relation to IgE sensitisation and window pane condensation. After a joint initiation phase, animals were divided into four different treatments quetapel 25 overdose on xanax with the combination of two concentrates (high vs low energy content) and management (access to outside park or not). ET can eliminate VUR, stop the symptoms and improve quality of life.