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Glioblastoma (GBM) is the most important primary brain tumor, both in terms of its incidence and its devastating impact on the unfortunate patients who have it. Nitric oxide production in murine spleen cells: role of interferons and prostaglandin E(2) in the generation of cytotoxic activity.

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The observed and expected WBC counts in WBC-reduced platelet samples correlated well at levels between approximately 5 and 1100 WBCs per counting area (5.0 x 10(2)-1.1 x 10(5)/mL). Analyses of the putative Crp/Fnr family of transcriptional regulators of a serotype 4b strain of Listeria monocytogenes. Effect of a thiobenzimidazolone derivative on DNA strand transfer catalyzed by HIV-1 reverse transcriptase. Administration of interferon-gamma to the cell culture increased HLA-DR and CD74, induced HLA-DM, but did not alter the expression of HLA-DO and induced HLA-DR release from the cells.

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The guanine nucleotide exchange factors Sec2 and PRONE: candidate synapomorphies for the Opisthokonta and the Archaeplastida. To conduct a cost-utility analysis to evaluate the cost effectiveness of dalteparin compared with UFH for preventing VTE in patients undergoing elective abdominal surgery. Numbers of mononuclear (MN) and polymorphonuclear (PMN) cells concentrated around the implants on PID 2 were larger in the chitin than control group. Tracing biological collections: between books and clinical trials. Evaluation of the polyene antibiotic filipin as a cytochemical probe for membrane cholesterol.

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Biological activities of the crude skin toxin of the Suez Gulf oriental catfish (Plotosus lineatus) and its antitumor effect in vivo (mice). These findings are consistent with the view that distorted hepatic blood flow has a significant role in elevating serum bile acid, at least in patients with moderately advanced liver cirrhosis. The spectral data are obtained by shaping the excitation pulse in order to control the relative phase between the weak resonant signal and the strong nonresonant background, in analogy with phase-contrast microscopy techniques.

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Congenital lacrimal system anomalies other than nasolacrimal duct obstruction are uncommon. Additionally, renal failure following nephrolithiasis was infrequent and not significantly different across the three cohorts. A search on Web of Science and Pubmed database including the keywords sleep, sleep deprivation, stress, hypothalamic-pituitary-adrenal axis, immune system, and autoimmune diseases. The development of a clinically durable small-diameter vascular graft as well as permanently implantable biosensors and artificial organ systems that interface with blood, including the artificial heart, kidney, liver, and lung, remain limited by surface-induced thrombotic responses.

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Even though the encoding of amplitude and directional information converged and activated the same neural substrate, our data thus show that additional and partly independent mechanisms are involved in bimanual amplitude as compared to that in directional control. Clinical symptoms often encompass severe nocturnal anal pruritus, when female worms deposit an abundance of eggs in the perianal region. Lymphocytes of dogs immunised with purified excreted-secreted antigens of Leishmania infantum co-incubated with Leishmania infected macrophages produce IFN gamma resulting in nitric oxide-mediated amastigote apoptosis.

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Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses. This series concerns 1 000 patients who where operated with heart-lung by-pass between 1974 and 1977. Associations of hypertension and its complications with variations in the xanthine dehydrogenase gene.

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The success of treatment of patients with cancer depends on establishing an accurate diagnosis. Fine needle aspiration cytology (FNAC) is an important tool in the investigation of thyroid nodules and has few reported complications. Phosphodiesterase (PDE) 4 is an enzyme that degrades intracellular cAMP.

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Analysis of immunoglobulin (Ig) variable (V) gene usage is beginning to provide answers to some of these questions. The ULSC calendar of synoptic conditions can be used to identify situations that lead to periods of extreme weather, i.e., heat waves, flooding and droughts, and to explore long-distance dispersal of airborne particles and biota across North America. Pipe is a Golgi-localized protein responsible for generating this spatial information during oogenesis through sulfation of unknown glycans.

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Taken together, our results suggest that seed predation is not independent of nectar robbing. In addition, transduction efficiencies of subgroup B Ad vectors do not decrease in the presence of anti-Ad5 antibodies, and seroprevalences of most subgroup B Ads are lower than that of Ad5, indicating that transduction with subgroup B Ad vectors is unlikely to be hampered by preexisting anti-Ad antibodies.

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Immunofluorescence study with laminin and neurofilament antisera. In this report, we show that the nuclear lamina can also play a role in the downregulation of heterochromatin and in gene activation. The present study has employed a mouse model with a lack of the low-molecular-weight neurofilament subunit (NFL-/-), in which formation of protein aggregates occurs in neurons, to investigate glial cellular reactions in the lumbar cord segments of NFL-/- mice at ages from 1 to 6 months.

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This historical analysis of public issues relating to smoking control in Western Australia examines relevant Western Australian state and Australian federal laws, their introduction, and their consequences. The compounds that elicited nymph behavioral responses were (E)-2-hexenal and 4-oxo-(E)-2-hexenal, while those that elicited adult behavioral responses were hexyl acetate and hexanal. The presence of the surfactant collectins, especially SP-D, in non-pulmonary tissues, such as the gastrointestinal tract and genital organs, suggest additional actions located to other mucosal surfaces. Retroviral vector-mediated in vitro expression of human soluble fas A new tool--the Combined Attention Test--was used for this purpose in a group of 41 unmedicated schizophrenia patients, divided into subgroups of patients with predominantly positive and negative symptoms, and 24 normal controls.

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In this paper, we review the known alterations of glucose and lactate metabolism that occur in patients with malignant tumors. We report that the major effect of ADAR2 is to reduce the expression of a large number of miRNAs, most of which act as onco-miRNAs. A brain stress response system is hypothesized to be activated by acute excessive drug intake, to be sensitized during repeated withdrawal, to persist into protracted abstinence, and to contribute to the compulsivity of addiction.

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Afferent stimulation of the right cardiac nerve at frequencies within the physiological firing range for unmyelinated C-fibre afferents induced an inhibition of net fluid absorption. In Podospora anserina, genes induced during this cell death reaction (idi genes) have been identified.

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The nematode Caenorhabditis elegans is the simplest animal model available to study human disease. We surveyed several methods for estimating the size and composition of the supergenome.

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Computer-tailored health education, a promising health education technique, is increasingly being delivered interactively, for example, over the Internet. The aim of present study was to evaluate the biomechanical behaviour of repairing osteochondral defect in rabbits which received a pulsed low-level gallium-arsenide (Ga-As) laser irradiation. Collection began June 4, 2004 and continued through September 24, 2004. We have validated a weighted numerical scoring system for the prioritization of such colorectal referrals in an attempt to rectify this, with detection of colorectal cancer (CRC) the primary outcome.

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The growth of the mutant virus can then be regulated by the degradation and splicing of the protein. The environmental performance of ethanol fuel system varies significantly with corn farming sites because of different crop management practices, soil properties, and climatic conditions. Laboratory evaluation of selected disinfectants as virucidal agents against porcine parvovirus, pseudorabies virus, and transmissible gastroenteritis virus.

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In this work we describe the cloning, expression, purification and characterization of rBmTI-6. These findings, based on the newly presented structure of the Globo H antigen, lend exciting and promising evidence for clinical advancement in the development of a therapeutic vaccine in the future. We review the superficial and deep venous anatomy of the lower extremity, introduce a pattern recognition approach for mapping of varicosities, and review the protocol for ultrasound evaluation for CVI. From June 2007 to September 2008, 152 patients underwent transcatheter aortic valve implantation at the German Heart Center, Munich (121 transfemorally, 26 transapically, and 5 through other sites of access).

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A series of 112 cases of bone grafting in secondary cleft lip and palate deformities is presented with a follow-up averaging 7.5 years. An assessment of the behaviour of prescribers, patients and pharmacies during the first year of generic substitution in Sweden.

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Research aim: The aim was to study the effects of early initiation of KMC on exclusive human milk feeding, growth, mortality, and morbidities in LBW neonates compared with late initiation of KMC during the hospital stay and postdischarge. Laser capture microdissection was used to isolate RNA from wound keratinocytes from incisional mouse skin wounds and adjacent normal skin keratinocytes.

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Our health care system at the crossroads: single payer or market reform? Despite being overrepresented among the poor, CLEP has not explicitly considered the situation of people with disabilities. Phenotypic classification of a prtTDelta deletion mutant revealed that expression of several major extracellular proteases is PrtT dependent, resulting in the inability to utilize protein as a nutritional source. Three phenylacyl-CoA ligase activities were detected in extracts of Pseudomonas putida CA-3 cells grown with a variety of aromatic carboxylic acids.