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A new bicyclic template has been developed for the synthesis of peptide mimetics. The increase of collagen synthesis in fibroblasts overexpressing LH2 (long) was independent from cross-linking as it was also observed in the presence of beta-aminopropionitril, a cross-linking inhibitor. Ten plasma proteins were identified and quantitated in the EDTA extracts.

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Deletion of agouti-related protein blunts ethanol self-administration and binge-like drinking in mice. Liver biopsies were obtained from 35 children with HFI, 14 contrast persons and 10 controls (of which 9 organ donors) and examined enzymatically. The prolongation of QT interval, involved in cardiac arrhythmia-related SUDEP, may be precipitated by antiepileptic drugs (AEDs). Ageing, hypogonadism, malnutrition, and the application of glucocorticoids have adverse effects on skeletal homeostasis. The study of long-term potentiation (LTP) has for many years been the centre of a raging debate as to whether the process is expressed by presynaptic or postsynaptic mechanisms.

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Androgen receptor gene CAG(n) trinucleotide repeats polymorphism in Chinese women with polycystic ovary syndrome. Thus, the secretion of serpins, which may be part of a bloodmeal complement inactivation system in tsetse, is used by procyclic trypanosomes to evade an influx of fresh trypanolytic complement with each bloodmeal. Cyclophosphamide-induced ovarian damage and stem cell factor expression in rat ovaries Acute ethanol administration increased splanchnic oxygen consumption in the control baboons, but the consequences of this effect on oxygenation of the perivenular zones were offset by a concomitant rise in blood flow, resulting in unchanged hepatic venous oxygen tensions.

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Prevalence and Specificity of RBC Alloantibodies in Indian Patients Attending a Tertiary Care Hospital. The syndrome most likely follows an autosomal recessive mode of inheritance. We have studied the mammalian homologue of Atg9p, a multi-spanning transmembrane protein essential in yeast for autophagy, to gain a better understanding of the function of this ubiquitious protein. On preoperative CBCT scans, curves delineating the cystic borders were drawn in all planes and the widest diameter (in millimeter), surface area (in square millimeter), and volume (in cubic millimeter) were calculated. A method for quantitatively estimating global displacement fields of coronary arterial vessel skeletons during cardiac cycles from X-ray coronary angiographic (CAG) image sequences is proposed.

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Testing the theoretical design of a health risk message: reexamining the major tenets of the extended parallel process model. While the total antioxidant capacity (TAC) of blood plasma is mainly accounted for by urate, TAC of cell interior can be expected to depend more on other antioxidants, especially glutathione and protein -SH groups. The results indicate that 5 J/cm(2) using 632.8 nm results in a stimulatory effect that is more effective than 830 and 1064 nm.

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Measurements of prolactin and androgens in patients with prostatic disease. To study the effects of noise on bioactivity of norepinephrine (NE) and cardiovascular system.

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Suppressive effect of deoxynivalenol, a Fusarium mycotoxin, on bovine and porcine neutrophil chemiluminescence: an in vitro study. Role of protein kinase C-Ras-MAPK p44/42 in ethanol and transforming growth factor-beta3-induced basic fibroblast growth factor release from folliculostellate cells.

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Increasing costs in discovering and developing new molecular entities and the continuing debate on limited company pipelines mean that pharmaceutical companies are under significant pressure to maximize the value of approved products. A successful implementation using the skills of physicians, nurses, biomedical engineers, computer scientists, and hospital administrators must be collaborative. However, no proton spectroscopic data of the subcortical gray matter are available in such disease. The impressive success in improving rice seed vigor through the over-expression of PIMT provides a valuable reference for engineering high-vigor seeds for crop production.

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The synthesis of a novel electrophoric derivatisation reagent, o-(pentafluorobenzyloxycarbonyl)-2,3,4,5-tetrafluorobenzoyl chloride, is described. Surgical treatment of an advanced chronic periodontitis affecting bridge abutments. These structural and cultural factors explain concentration of expectation, resource, and RCT productivity in medical science.

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RPE65 is the visual cycle retinol isomerase and missense mutations in its gene cause severe retinal dystrophies in man, due to lack of chromophore. This study aimed to compare fatigue severity among survivors of different cancer types with a normative population and also to identify variations in fatigue among cancer survivors according to clinical and demographic variables. Herpes simplex virus types 1 and 2, and cytomegalovirus antibodies in serum and CSF.

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In sera of patients suffering from an exacerbation of systemic lupus erythematosus (SLE), increased amounts of abnormal C1q were detected, contrasting with decreased or even undetectable levels of normal C1q in these sera. Western Blot using monoclonal antiphosphoserine antibody showed that BCKA induced increased immunocontent of phosphoserine-containing amino acids in several proteins in total cell homogenate. A comparison between the number and distribution of functioning eccrine sweat glands in Europeans and Africans. While lower socioeconomic status is implicated in growth retardation at higher altitudes, the smaller stature in adults in well-off communities says otherwise.

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To study the immunoregulatory function of Silky Chicken-Gastrodia Elata Blume nutrient solution in mice. 2HG accumulation detected by 3.0-tesla MRS not only correlates well with IDH status, but also positively correlates with survival in WHO grade II and III gliomas. Tubercidin and ara-A, analogs of adenosine, were the most potent of the tested growth inhibitors with amebistatic concentrations of about 0.6 and 3.0 microM, respectively.

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These preliminary findings raise the possibility that patient and caregiver self-efficacy for managing pain, symptoms, and function may be important factors affecting adjustment, and that interventions targeted at increasing self-efficacy may be useful in this population. General anesthesia for surgery influences melatonin and cortisol levels.

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beta-carotene levels showed a tendency to be lower in women who developed cancer than in controls (36 micrograms l-1 among cases compared with 50 micrograms l-1 among controls) but the difference was not statistically significant. The incidence of malignant pleural mesothelioma (MPM) is associated with exposure to asbestos, and projections suggest that the yearly number of deaths in Western Europe due to MPM will increase until 2020.

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Stimulation of Eryptosis, the Suicidal Erythrocyte Death by Piceatannol. Regeneration and maintenance of the planarian midline is regulated by a slit orthologue. By selective fluorescence labeling and proteomic analysis, we have identified this residue as cysteine-39 of the mitochondrially encoded ND3 subunit of bovine heart mitochondria.

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The standard diffusion tensor model is limited in its ability to provide detailed information about multidirectional fiber architecture in human white matter. Modulation of renin-angiotensin system and arterial stiffness: evidence from clinical trials. The curarimimetic activity of some quaternary ammonium salts derived from dienestrol We conducted literature searches restricted to the English language for studies on CAM as monotherapy in depression.

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