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Hysterocolpectomy with colpocleisis for massive genital prolapse in women aged over 70 years. Molecular characterization of resistance-nodulation-division transporters from solvent- and drug-resistant bacteria in petroleum-contaminated soil. Both groups, however, showed excellent overall functional results. Third, cornstarch induces peritoneal adhesion formation and granulomatous peritonitis.

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Cardiomyocytes synthesized HA but only when stimulated by PDGF-BB, whereas fibroblasts synthesized HA without addition of growth factors as well as when stimulated by any of the three growth factors. An unexpected finding in the patient who also had a hypothalamic embryonal cell carcinoma and hypocortisolism was an extremely high concentration of a biologically inactive adrenocorticotropic like substance in the CSF.

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Qinimycins showed weak antimicrobial activity against Gram-positive bacteria. Although the molecular biology of transposition is starting to be understood, the external factors that influence its frequency have not yet been studied in any detail. Expression of an antigen, recognized by a monoclonal antibody raised against PC13 embryonal carcinoma, is described in mouse preimplantation embryogenesis. The results in patients with post-traumatic arthritis were poor.

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Bid cleavage and dissipation of mitochondrial membrane potential (delta psi(m)) verified the involvement of mitochondria. It is pointed out that the intraglandular activation of the precursors for both lipolytic and proteolytic enzymes seems to be essential for the initiating mechanisms of the disease. Effects of cytochalasin B and of deoxyglucose on phagocytosis-related changes in membrane potential in rat peritoneal macrophages. Our results suggest that unilateral lung volume reduction is a suitable option for patients with distinct heterogeneity of emphysema between lungs.

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Neonatal jaundice is the most frequently encountered diagnostic and therapeutic problem in the newborn. There have been significant advances in the past several years with regard to targeted therapy and immunotherapy for cancer.

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Leukodystrophy patients manifest many of the same symptoms and medical complications despite the wide spectrum of genetic origins. Skills in handling turbuhaler, diskus, and pressurized metered-dose inhaler in korean asthmatic patients. Our findings add biological support to the notion that obesity is associated with slower and more variable RTs. Recurrence of cardiac arrest after 14 years without ICD interventions: a VF cluster immediately after delivery.

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Non-covalent streptavidin-biotin interactions were employed to link biotin-PNA to biotin-MIL-88A particles mediated by streptavidin. The incidence of sport-related injuries seems to be influenced by such factors as somatic features, jumping parameters and the length of professional volleyball career. The present investigation was performed to determine whether identical changes are induced by systemic photochemotherapy using 8-methoxypsoralen and UVA (PUVA) under therapeutic conditions. Vocal cord injuries, postoperative hoarseness, and sore throat are common complications after general anesthesia. In addition, we show that 2-mercaptoethanol suppresses short time-scale intermittency (1 ms to 1 s) in quantum dot fluorescence by reducing time spent in the off-state.

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The other patient had no mutations in any of the exonic sequences of the gene, but she did have a novel base substitution in intron 13. A broad range of nanomedicines is being developed to improve drug delivery for CNS disorders. Current status of the physiopathology of pernicious malaria attacks The results demonstrated a dose-dependent inhibition by quinapril of serum and tissue ACE activities and neointima formation. Patients with low expression levels receiving erythropoietin seemed to do better than patients with higher expression levels or not receiving erythropoietin.

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The results showed that platinums (cisplatin, carboplatin, oxaliplatin) are more universally effective than other chemotherapeutic drugs (doxorubicin, epi-doxorubicin, 5-flourouracil, mitomycin, cyclophosphamide, vincristine and vinorelbine) to enhance the response of six human epithelial tumor cell lines (A375, Bcap37, NCI-H157, SW480, BGC-823 and HeLa) to LTalpha. Concentration and size distribution of insulin-like growth factor-I in human normal and osteoarthritic synovial fluid and cartilage.

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Perturbing CDK5RAP2 function delocalized gamma-tubulin from the centrosomes and inhibited centrosomal microtubule nucleation, thus leading to disorganization of interphase microtubule arrays and formation of anastral mitotic spindles. New developments in the use of peptide gonadotropin-releasing hormone antagonists versus agonists.

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Measuring patient safety in ambulatory care: potential for identifying medical group drug-drug interaction rates using claims data. Our results suggest that Mst1 plays an important role in the induction of apoptosis of VSMCs, mediating the vascular remodeling process, and may be a potential therapeutic target for vascular proliferative diseases. Importantly, genotoxic stress to cancer cells that resulted in activation of p53 also upregulated the expression of Notch1. Higher plasma fibrinogen and D-dimer concentrations may be associated with the presence of AAA.

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Open radical nephroureterectomy has been the standard treatment for upper urinary tract transitional cell carcinoma (TCC). Incidence of spina bifida occulta in relatives of children with myelodysplasia. A total of 178 PCOS patients fulfilling Rotterdam criteria and 100 BMI-matched controls participated in the study.

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Expression of recombinant proteins in a lipid A mutant of Escherichia coli BL21 with a strongly reduced capacity to induce dendritic cell activation and maturation. An outbreak of Lawsonia intracellularis infection in a standardbred herd in Ontario.

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Randomly chosen clones of the murine K-1735 melanoma tumor were used by Raz and Geiger to address the question of whether variations in actin organization in these cells may be related to their lung colonization capability in syngeneic hosts (Cancer Res., 42: 5183-5190, 1982). The rapid increases in energy costs, which began in the 1970s, created financial incentives to upgrade to this more expensive and maintenance-intensive method of aeration. Gender of respondent does not affect the psychometric properties of the Brazilian Household Food Security Scale.

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In these nonlinear photon-interference experiments the time resolution is determined by the correlation time of the light source rather than its pulse width. We hypothesised that an impairment of muscle energy metabolism can participate in this increased energy expenditure. The estimation of virtually safe dose (VSD) is regarded as a component of the third phase. CD44 variant isoforms are expressed on normal epithelial cells in a different pattern.

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This hypothesis is discussed in the light of observations suggesting a co-regulation of apoptosis and autophagy in mammalian cells. Basal adenylate cyclase activity, however, was slightly inhibited by lithium in human platelets. Using a reverse-transcription polymerase chain reaction (RT-PCR)-based assay, connexin (Cx) 26, connexin (Cx) 32 and connexin (Cx) 43 mRNAs were determined prospectively in noncancerous liver tissues from these 79 patients and in the liver tissues from 15 controls.

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Since the prevalence of these polymorphisms could be race-related, and no data exist about the frequency of these polymorphisms in the Chilean population, the aim of the current study was to investigate the association of the interleukin-1 gene polymorphisms with aggressive periodontitis (AgP). We show that this reaction involves isomerization to a nerolidyl pyrophosphate intermediate followed by bond rotation prior to attack by the nucleophile. The findings from this study suggest that harm reduction programs need to target (noninjecting) drug users, and that existing social networks could be creatively used to extend the reach of these programs. The secretory epithelial cells were found to be of three types: (a) mucus-producing cells, (b) protein-secreting cells, and (c) cells intermediate between (a) and (b). By use of selective agonists and antagonists it is concluded that acetylcholine interacts with muscarinic receptors in the serosal membrane.

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The sensitivity of the ventilatory response to carbon dioxide in hyperoxia during light (25 W) exercise was compared to that at rest in 14 volunteers. This article examines the role of arrhythmogenic right ventricular cardiomyopathy/dysplasia in causing sudden death in young competitive athletes and suggests a prevention strategy based on identification of affected athletes at preparticipation screening. (1) There is increasing evidence that the cerebral endothelium and the blood-brain barrier (BBB) plays an important role in the oxidative stress-induced brain damage.

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In the current study, we performed biochemical analyses to determine the stage in the viral life cycle blocked by IFN-gamma-induced NO. Fludarabine plus cyclophosphamide for the treatment of advanced chronic lymphocytic leukemia. In animal investigations even short hypoxic exposure, continuously or in short repeated episodes mimicking obstructive sleep apnoea (OSA), leads to pulmonary artery remodelling and to pulmonary hypertension (PH).

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