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The objectives of this phase I trial were to determine the dose-limiting toxicities (DLTs) of the novel topoisomerase I inhibitor topotecan combined with cisplatin, to define the maximum-tolerated doses (MTDs) of the combination without and with the use of filgrastim, and to define recommended doses for phase II trials. Different procedures have been described to treat different stages of this disease. Since the pharmacologic effect of NO and DNP was only transient, our data suggest that even a brief period of focal energy restriction can trigger Wallerian degeneration. Locally derived reference values are important to avoid false positive or false negative findings during work-up in patients evaluated for osteoporosis.

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After 20 courses, a partial response was achieved and she underwent curative operation with partial resection for 4 metastatic legions and RFA for others. The sec24-1 Deltasfb2 Deltasfb3 mutant grew slower than sec24-1. Parasite specific antibodies in three strains of mice after infection with Trypanosoma cruzi.

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These observations indicate that the rate of bone resorption in inflammation-induced bone loss may not be due to a single factor but to the concerted action of several local or systemic factors. Dose measurements were performed with thermoluminescent dosimeters. Caveats to the use of parenteral methotrexate in the treatment of rheumatic disease.

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The 1996-1997 and the 1998-1999 rounds of the nationally representative Community Tracking Study Household Survey. In a patient with a distally migrated metallic stent, trimming of the stent is possible by means of an APC. It has been shown that the donor and acceptor sides of the photosynthetic reaction centre are organized functionally in such a way that temporal behaviour of oxidized (reduced) forms of the donor carriers of the reaction centre is absolutely similar to that of the carriers located on the acceptor side of the reaction centre. The total synthesis of (-)-jorumycin (1) and (-)-renieramycin G (2) has been accomplished in 25 and 23 steps, respectively, from 5-benzyloxy-2,4-dimethoxy-3-methyl-benzyl alcohol. 43 deaths are known to have occurred among the 17 032 participants in the Oxford/Family Planning Association contraceptive study up to the end of April, 1977.

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Small lesions involving only the MPN and OVLT or the MPN and caudally adjacent loci in the suprachiasmatic region were as effective in this respect as larger lesions encompassing most of the preoptic-suprachiasmatic region from the diagonal band of Broca to the rostral pole of the SCN. In addition, a smooth potential for the polymer-surface interactions is also implemented for comparison to the same interactions currently modeled by elastic collision. Antihypertensive mechanism of the diuretic muzolimine in mild renal failure. Palonosetron at doses of 0.25 and 0.75 mg was shown to be effective in preventing chemotherapy-induced nausea and vomiting with high CR rates of patients treated with HEC in Japan.

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To construct a life-sized eye model using the three-dimensional (3D) printing technology for fundus viewing study of the viewing system. In this article we outline the different schools of new institutionalism and a few other selected political science theories. Can we extract useful and scientifically sound information from retrospective nonrandomized trials to be applied in orthodontic evidence-based practice treatments?

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Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) play an important role in the development and maintenance of male and female gonads. In obstructive HCM patients who underwent SM, left ventricular mechanics (echocardiographic longitudinal systolic strain and diastolic strain rates), assessed at the basal septum (myocardium removed during myectomy) and histopathologic findings characteristic for HCM (disarray and fibrosis) were significantly associated with in vitro myocardial resting and developed contractile performance. Assessment of myocardial perfusion with real-time myocardial contrast echocardiography: methodology and clinical applications. The purified particles are different from the known avian RNA tumor viruses in their protein composition and their sedimentation constant.

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In two studies with blueberry or grape, additional macronutrients (carbohydrate, fat, protein) were included in the control and treatment meals. These hybrid phages would therefore be useful vectors for cloning foreign DNA fragments generated by cleavage with BamHI or HaeIII endonucleases. These antigens are transferred and immobilized on a nitrocellulose sheet.

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We developed and tested ocular inserts containing epidermal growth factor (EGF) for a causal treatment of keratoconjunctivitis sicca (KCS). The V2 segment Doppler sonography measurements may guide future examinations and provide essential information regarding the proximally deployed stent. All posts had a diameter of 1.4 mm and a length of 13 mm and were cemented 8 mm within the root canal with self-adhesive universal resin cement. This enhancer is contained within a 761-bp DNA fragment that encompasses a newly identified Exon of myo7aa and whose activity does not depend on orientation. Consideration of the scale at which communities are defined both taxonomically and spatially can reconcile apparently contradictory results on the extent to which plants show phylogenetic niche conservatism.

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These include the historical predecessors, the current protocols with examples, future directions for the software, and discussion of research systems with different architectures. These effects of endogenous opioid peptides were prevented by naloxone, indicating opiate receptors were required for the biologic response.

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In this review, we discussed on recent findings concerning the role of different angiotensin peptides in the pathophysiology of ACS and coronary atherothrombosis, exploring the link between these molecules and atherosclerotic plaque vulnerability. These studies indicate that the neural circuitry mediating VSPA is contained within the caudal brainstem and spinal cord, since decerebration did not reduce VSPA when compared with sham-operated controls.

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Genomic changes in the E2/NS1 region of HCV before and after IFN therapy in relation to clinical course When rabbit detrusor muscle strips were superfused with medium containing firefly luciferin-luciferase and stimulated transmurally at low stimulation parameters, tetrodotoxin-sensitive contractions were obtained but no release of ATP could be detected.

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A case of qualitative platelet dysfunction following cancer chemotherapy is documented. Using Flat-Panel Perfusion Imaging to Measure Cerebral Hemodynamics: A Pilot Feasibility Study in Patients With Carotid Stenosis.

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Family Caregivers of Persons With Spinal Cord Injury: Predicting Caregivers at Risk for Probable Depression. Evaluation of the cytotoxicity effect of dimethyl sulfoxide (DMSO) on Caco2/TC7 colon tumor cell cultures. A complete separation has been achieved by adsorbing (66,67)Ga and a lesser amount of bulk cobalt at pH 3 on Fe-CA beads, followed by desorbing cobalt from the beads with 0.4M NaNO(2).

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